What do systematic reviews say?

Intervention not reported

• Integrated versus non‐integrated orbital implants for treating anophthalmic sockets 2016 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 100 participants
  Very low

Pyridoxine vs placebo

Pyridoxine showed no clear difference in interventions side effects: headaches compared with placebo (low certainty).

• Interventions for treating hyperemesis gravidarum 2016 · Cochrane Headline outcomes only
  RR 1.33 [0.52, 3.42]
  1 study · 66 participants
  Low

Children: prednisolone vs dexamethasone

• Different oral corticosteroid regimens for acute asthma 2016 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 533 participants
  GRADE not reported

CRISIS INTERVENTION vs usual care

• Crisis intervention for people with severe mental illnesses 2015 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 226 participants
  Low

Intervention not reported

The intervention showed no clear difference in retention on treatment Duration of retention on treatment was not… (moderate certainty).

• Pharmacological interventions for epilepsy in people with intellectual disabilities 2015 · Cochrane Headline outcomes only
  RR 1.43 [0.76, 2.69]
  3 studies · 310 participants
  Moderate

Intervention not reported

The intervention probably leads to lower block success (supplementation or conversion to general anaesthesia (moderate certainty).

• Ultrasound guidance for upper and lower limb blocks 2015 · Cochrane Headline outcomes only
  OR 0.28 [0.2, 0.39]
  18 studies · 1807 participants
  Moderate

Intervention not reported

It is very uncertain whether the intervention changes paraesthesia (very low certainty).

• Ultrasound guidance for upper and lower limb blocks 2015 · Cochrane Headline outcomes only
  OR 0.42 [0.23, 0.76]
  6 studies · 471 participants
  Very low

Intervention not reported

The intervention probably leads to higher pain score for highest level before leaving clinic (100 mm VAS) (moderate certainty).

• Interventions for pain with intrauterine device insertion 2015 · Cochrane Headline outcomes only
  MD 7.6 [6.48, 8.72]
  105 participants
  Moderate

Summary of findings table 3: comparison of operation types: firebreak skin grafting vs z‐plasty closure of fasciectomy

• Surgery for Dupuytren's contracture of the fingers 2015 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 79 participants
  Low

Summary of findings table 1: comparison of operation types: early results of needle fasciotomy vs limited fasciectomy

• Surgery for Dupuytren's contracture of the fingers 2015 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 117 participants
  Low

Lidocaine vs lidocaine with adrenaline

• Adrenaline with lidocaine for digital nerve blocks 2015 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 20 participants
  Low

GnRH‐a + raloxifene vs GnRH‐a ± placebo

• Add‐back therapy with GnRH analogues for uterine fibroids 2015 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 91 participants
  Low

Summary of findings ‐ Intravenous lorazepam vs intravenous diazepam

Lorazepam IV probably leads to lower continuation of status requiring a different drug or general… compared with diazepam IV (moderate certainty).

• Anticonvulsant therapy for status epilepticus 2014 · Cochrane Headline outcomes only
  RR 0.63 [0.45, 0.88]
  3 studies · 264 participants
  Moderate

Primary comparison for continuous passive motion (CPM) vs no CPM

It is very uncertain whether primary comparison for continuous passive motion (CPM) changes manipulation under anaesthesia Counts of manipulation under… compared with no CPM (very low certainty).

• Continuous passive motion following total knee arthroplasty in people with arthritis 2014 · Cochrane Headline outcomes only
  RR 0.34 [0.13, 0.89]
  8 studies · 581 participants
  Very low

Exercise vs control

• Exercise for vasomotor menopausal symptoms 2014 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 454 participants
  Low

Exercise vs yoga

• Exercise for vasomotor menopausal symptoms 2014 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 279 participants
  Low

Computer‐assisted reconstruction surgery vs conventional operating techniques

• Computer‐assisted surgery for knee ligament reconstruction 2014 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 40 participants
  Very low

SULPIRIDE vs placebo

• Sulpiride versus placebo for schizophrenia 2014 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 18 participants
  Very low

SULPIRIDE vs placebo

• Sulpiride versus placebo for schizophrenia 2014 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 18 participants
  Very low

Intervention not reported

• Relaxation for perimenopausal and postmenopausal symptoms 2014 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 72 participants
  Very low