Short‐term (1 week) change in isolated movement, objective and subjective measures of speech production SARA. Scale from: 0 to 6. Higher scores indicate more severe speech disorder. · people with speech disorder resulting from hereditary ataxias
1 finding from 1 review
Macrovascular complications · persons with type 1 diabetes mellitus
1 finding from 1 review
no estimate extracted
Studies not reported
Low
Intervention not reported
Any intracranial disease progression at 1 year · Patients with brain metastases
The intervention may leads to lower any intracranial disease progression at 1 year (low certainty).
1 finding from 1 review
Gingivitis · Adults, 16 years and older (dentate)
Interdental brushing plus toothbrushing may leads to lower gingivitis (bleeding and gingival indices; standardised across… compared with flossing plus toothbrushing (low certainty).
Plaque · Adults, 16 years and older (dentate)
Interdental brushing plus toothbrushing showed no clear difference in plaque (plaque indices; standardised across indices) compared with flossing plus toothbrushing (low certainty).
Intervention not reported
ACR50 American College of Rheumatology 50% improvement criteria · participants with rheumatoid arthritis and with a partial response to DMARDs
The intervention probably leads to higher ACR50 American College of Rheumatology 50% improvement criteria (moderate certainty).
1 finding from 1 review
Intervention not reported
Outcome: ACR50 ‐ American College of Rheumatology Improvement Criteria · participants with rheumatoid arthritis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
ACR50 American College of Rheumatology improvement criteria · participants with rheumatoid arthritis and with partial response to MTX
The intervention probably leads to higher ACR50 American College of Rheumatology improvement criteria (moderate certainty).
1 finding from 1 review
Intervention not reported
Non‐fatal macrovascular outcomes 1. Composite a. Intervention vs metformin [1a. 6 months to 4 years] b. Intervention vs thiazolidinediones [1b. 52 weeks to 4 years] c. Intervention vs meglitinide [1c. 12 months to 15 months]2. Non‐fatal myocardial... · participants with type 2 diabetes mellitus
The intervention may leads to lower non‐fatal macrovascular outcomes 1. Composite a. Intervention vs… (low certainty).
1 finding from 1 review
RR 0.67 [0.48, 0.93]
1 study · 3 participants
Low
Intervention not reported
Macrovascular outcomes · participants with type 2 diabetes mellitus
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
Non‐fatal macrovascular outcomes 1. Composite 2. Non‐fatal myocardial infarction Intervention vs insulin [4.75 years to 10.0 years] · participants with type 2 diabetes mellitus
The intervention showed no clear difference in non‐fatal macrovascular outcomes 1. Composite 2. Non‐fatal… (low certainty).
1 finding from 1 review
RR 1.08 [0.81, 1.45]
1 study · 2 participants
Low
Intervention not reported
Amphetamine use (UA) Negative urinalyses across the study · Amphetamine abuse or dependence
1 finding from 1 review
Intervention not reported
Mean improvement in pure‐tone average hearing threshold across all frequencies Decibels Scale from: 0 to 120 · patients with idiopathic sudden sensorineural hearing loss or tinnitus
1 finding from 1 review
Intervention not reported
ACR 50% improvement ‐ not measured · patients with treating rheumatoid arthritis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
ACR 50% improvement ( · patients with Rheumatoid arthritis
The intervention showed no clear difference in ACR 50% improvement ( (low certainty).
1 finding from 1 review
Intervention not reported
Speed outcomes measured: Mean speed, 85th percentile speed, percentage of vehicles over the speed limit and percentage exceeding the speed limit by more than 15mph. Speed results across all new camera sites included a 2.3mph reduction (6% reductio...
1 finding from 1 review
no estimate extracted
Studies not reported
Moderate
Intervention not reported
Crash outcomes measured: Killed and seriously injured (KSIs) and personal injury crashes (PICs). Across all sites KSI's decreased by 42%. This equated to about 1700 fewer KSI's per annum at these camera sites. Fixed cameras in both urban (47% redu...
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
Having controlled for season and general trends, injury crash outcomes in experimental areas relative to control areas were a net reduction of 11% (p= 0.03) in all crashes and 19% (p=0.002) in injury crashes on open roads across the region associa...
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
ACR‐50 · patients with rheumatoid arthritis
1 finding from 1 review
ACR50% improvement criteria · patients with rheumatoid arthritis
Tocilizumab 8 mg/kg + MTX/DMARD leads to higher ACR50% improvement criteria compared with placebo + MTX/DMARD (high certainty).
1 finding from 1 review