Gap finder

Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

1,645 questions in 107 reviews · Wounds

current versions
No studies 651 · 39.6%Ungraded 84 · 5.1%Very low 554 · 33.7%Low 283 · 17.2%Moderate 64 · 3.9%High 9 · 0.5%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Summary of findings table ‐ Energy, protein and micronutrients vs standard diet
Acceptability of nutritional supplements ‐ not reported · inpatients who are mildly or seriously malnourished or at risk of being malnourished, elderly patients at risk of…
Nutritional interventions for preventing and treating pressure ulcers (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Arginine and micronutrients vs standard diet
Change in pressure ulcer area (percentage) · malnourished patients with pressure ulcers
Nutritional interventions for preventing and treating pressure ulcers (2024) · Cochrane
no estimate extracted2 studies · 231 participantsLow
Summary of findings table ‐ Arginine and micronutrients vs standard diet
Acceptability of nutritional supplements: non‐adherence · malnourished patients with pressure ulcers
Nutritional interventions for preventing and treating pressure ulcers (2024) · Cochrane
RR 15.6 [0.94, 259]1 study · 49 participantsVery low
Summary of findings table ‐ Arginine and micronutrients vs standard diet
Side effects: at least one adverse gastrointestinal event · malnourished patients with pressure ulcers
Nutritional interventions for preventing and treating pressure ulcers (2024) · Cochrane
RR 1.54 [0.36, 6.64]3 studies · 282 participantsVery low
Summary of findings table ‐ Arginine and micronutrients vs standard diet
Costs (EUR) · malnourished patients with pressure ulcers
Nutritional interventions for preventing and treating pressure ulcers (2024) · Cochrane
no estimate extracted1 study · 138 participantsModerate
Summary of findings table ‐ Arginine and micronutrients vs standard diet
Health‐related quality of life ‐ not reported · malnourished patients with pressure ulcers
Nutritional interventions for preventing and treating pressure ulcers (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Collagen vs standard diet or placebo
Pressure ulcers healed ‐ not reported · adult inpatients or outpatients with pressure ulcers
Nutritional interventions for preventing and treating pressure ulcers (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Collagen vs standard diet or placebo
Time to complete healing of pressure ulcers ‐ not reported · adult inpatients or outpatients with pressure ulcers
Nutritional interventions for preventing and treating pressure ulcers (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Collagen vs standard diet or placebo
Change in pressure ulcer area (cm²) · adult inpatients or outpatients with pressure ulcers
Nutritional interventions for preventing and treating pressure ulcers (2024) · Cochrane
no estimate extracted1 study · 74 participantsModerate
Summary of findings table ‐ Collagen vs standard diet or placebo
Acceptability of nutritional supplements ‐ not reported · adult inpatients or outpatients with pressure ulcers
Nutritional interventions for preventing and treating pressure ulcers (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Collagen vs standard diet or placebo
Side effects: at least one adverse event · adult inpatients or outpatients with pressure ulcers
Nutritional interventions for preventing and treating pressure ulcers (2024) · Cochrane
RR 2.69 [0.33, 22.3]2 studies · 154 participantsVery low
Summary of findings table ‐ Energy, protein and micronutrients vs standard diet
Side effects ‐ not reported · inpatients who are mildly or seriously malnourished or at risk of being malnourished, elderly patients at risk of…
Nutritional interventions for preventing and treating pressure ulcers (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Collagen vs standard diet or placebo
Costs ‐ not reported · adult inpatients or outpatients with pressure ulcers
Nutritional interventions for preventing and treating pressure ulcers (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Collagen vs standard diet or placebo
Health‐related quality of life ‐ not reported · adult inpatients or outpatients with pressure ulcers
Nutritional interventions for preventing and treating pressure ulcers (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Energy, protein and micronutrients vs standard diet
Costs ‐ not reported · inpatients who are mildly or seriously malnourished or at risk of being malnourished, elderly patients at risk of…
Nutritional interventions for preventing and treating pressure ulcers (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Energy, protein and micronutrients vs standard diet
Health‐related quality of life ‐ not reported · inpatients who are mildly or seriously malnourished or at risk of being malnourished, elderly patients at risk of…
Nutritional interventions for preventing and treating pressure ulcers (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Protein vs standard diet
Incidence of pressure ulcers · patients (> 65 years) following hip fracture; patients with a recent stroke
Nutritional interventions for preventing and treating pressure ulcers (2024) · Cochrane
RR 0.75 [0.49, 1.14]4 studies · 4264 participantsLow
Summary of findings table ‐ Protein vs standard diet
Time to pressure ulcer development ‐ not reported · patients (> 65 years) following hip fracture; patients with a recent stroke
Nutritional interventions for preventing and treating pressure ulcers (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Protein vs standard diet
Acceptability of nutritional supplements ‐ not reported · patients (> 65 years) following hip fracture; patients with a recent stroke
Nutritional interventions for preventing and treating pressure ulcers (2024) · Cochrane
no estimate extractedNRNo studies
Dextranomer beads (autolytic) vs Eusol gauze
Time to a clean wound bed ( · adults with surgical wounds
Debridement for surgical wounds (2024) · Cochrane
no estimate extracted1 study · 20 participantsVery low
Dextranomer paste (autolytic) vs 10% aqueous polyvinylpyrrolidone
Proportion of wounds completely healed · adults with surgical wounds
Debridement for surgical wounds (2024) · Cochrane
no estimate extractedNRNo studies
Dextranomer paste (autolytic) vs 10% aqueous polyvinylpyrrolidone
Time to complete healing (days) · adults with surgical wounds
Debridement for surgical wounds (2024) · Cochrane
no estimate extractedNRNo studies
Dextranomer paste (autolytic) vs 10% aqueous polyvinylpyrrolidone
Serious adverse events: life‐threatening/ hospitalisation · adults with surgical wounds
Debridement for surgical wounds (2024) · Cochrane
no estimate extracted1 study · 40 participantsLow
Dextranomer paste (autolytic) vs 0.1% chloramine‐soaked dressings
Time to a clean wound bed ( · adults with surgical wounds
Debridement for surgical wounds (2024) · Cochrane
no estimate extracted1 study · 28 participantsVery low
Dextranomer paste (autolytic) vs 0.1% chloramine‐soaked dressings
Proportion of wounds completely debrided · adults with surgical wounds
Debridement for surgical wounds (2024) · Cochrane
no estimate extractedNRNo studies
Dextranomer paste (autolytic) vs 0.1% chloramine‐soaked dressings
Rate of reduction in wound size · adults with surgical wounds
Debridement for surgical wounds (2024) · Cochrane
no estimate extractedNRNo studies
Dextranomer paste (autolytic) vs 0.1% chloramine‐soaked dressings
Proportion of wounds completely healed · adults with surgical wounds
Debridement for surgical wounds (2024) · Cochrane
no estimate extractedNRNo studies
Dextranomer paste (autolytic) vs 0.1% chloramine‐soaked dressings
Time to complete healing (days) · adults with surgical wounds
Debridement for surgical wounds (2024) · Cochrane
no estimate extracted1 study · 28 participantsVery low
Dextranomer paste (autolytic) vs 0.1% chloramine‐soaked dressings
Serious adverse events: life‐threatening/ hospitalisation · adults with surgical wounds
Debridement for surgical wounds (2024) · Cochrane
no estimate extracted1 study · 28 participantsLow
Dextranomer beads (autolytic) vs silicone foam elastomer (autolytic)
Time to a clean wound bed · adults with surgical wounds
Debridement for surgical wounds (2024) · Cochrane
no estimate extractedNRNo studies
Dextranomer beads (autolytic) vs Eusol gauze
Proportion of wounds completely debrided · adults with surgical wounds
Debridement for surgical wounds (2024) · Cochrane
no estimate extractedNRNo studies
Dextranomer beads (autolytic) vs silicone foam elastomer (autolytic)
Proportion of wounds completely debrided · adults with surgical wounds
Debridement for surgical wounds (2024) · Cochrane
no estimate extractedNRNo studies
Dextranomer beads (autolytic) vs silicone foam elastomer (autolytic)
Rate of reduction in wound size · adults with surgical wounds
Debridement for surgical wounds (2024) · Cochrane
no estimate extractedNRNo studies
Dextranomer beads (autolytic) vs silicone foam elastomer (autolytic)
Proportion of wounds completely healed · adults with surgical wounds
Debridement for surgical wounds (2024) · Cochrane
no estimate extractedNRNo studies
Dextranomer beads (autolytic) vs silicone foam elastomer (autolytic)
Time to complete healing (days) · adults with surgical wounds
Debridement for surgical wounds (2024) · Cochrane
no estimate extracted1 study · 50 participantsVery low
Dextranomer beads (autolytic) vs silicone foam elastomer (autolytic)
Serious adverse events: life‐threatening/ hospitalisation · adults with surgical wounds
Debridement for surgical wounds (2024) · Cochrane
no estimate extractedNRNo studies
Streptokinase/streptodornase (enzymatic) vs saline‐soaked dressing
Time to a clean wound bed ( · adults with surgical wounds
Debridement for surgical wounds (2024) · Cochrane
no estimate extracted1 study · 21 participantsLow
Streptokinase/streptodornase (enzymatic) vs saline‐soaked dressing
Proportion of wounds completely debrided · adults with surgical wounds
Debridement for surgical wounds (2024) · Cochrane
no estimate extractedNRNo studies
Streptokinase/streptodornase (enzymatic) vs saline‐soaked dressing
Rate of reduction in wound size · adults with surgical wounds
Debridement for surgical wounds (2024) · Cochrane
no estimate extractedNRNo studies
Streptokinase/streptodornase (enzymatic) vs saline‐soaked dressing
Proportion of wounds completely healed · adults with surgical wounds
Debridement for surgical wounds (2024) · Cochrane
no estimate extractedNRNo studies
Streptokinase/streptodornase (enzymatic) vs saline‐soaked dressing
Time to complete healing (days) · adults with surgical wounds
Debridement for surgical wounds (2024) · Cochrane
no estimate extractedNRNo studies
Dextranomer beads (autolytic) vs Eusol gauze
Rate of reduction in wound size · adults with surgical wounds
Debridement for surgical wounds (2024) · Cochrane
no estimate extractedNRNo studies
Streptokinase/streptodornase (enzymatic) vs saline‐soaked dressing
Serious adverse events: life‐threatening/ hospitalisation · adults with surgical wounds
Debridement for surgical wounds (2024) · Cochrane
no estimate extracted1 study · 21 participantsVery low
Surgical debridement via an endoscopic method vs conventional 'open' surgical debridement
Time to a clean wound bed (minutes) · adults with surgical wounds
Debridement for surgical wounds (2024) · Cochrane
no estimate extracted1 study · 106 participantsVery low
Surgical debridement via an endoscopic method vs conventional 'open' surgical debridement
Proportion of wounds completely debrided · adults with surgical wounds
Debridement for surgical wounds (2024) · Cochrane
no estimate extractedNRNo studies
Surgical debridement via an endoscopic method vs conventional 'open' surgical debridement
Rate of reduction in wound size · adults with surgical wounds
Debridement for surgical wounds (2024) · Cochrane
no estimate extractedNRNo studies
Surgical debridement via an endoscopic method vs conventional 'open' surgical debridement
Proportion of wounds completely healed · adults with surgical wounds
Debridement for surgical wounds (2024) · Cochrane
no estimate extractedNRNo studies
Surgical debridement via an endoscopic method vs conventional 'open' surgical debridement
Time to complete healing ( · adults with surgical wounds
Debridement for surgical wounds (2024) · Cochrane
no estimate extracted1 study · 106 participantsLow
Surgical debridement via an endoscopic method vs conventional 'open' surgical debridement
Serious adverse events: life‐threatening/ hospitalisation · adults with surgical wounds
Debridement for surgical wounds (2024) · Cochrane
no estimate extractedNRNo studies
Dextranomer beads (autolytic) vs Eusol gauze
Proportion of wounds completely healed · adults with surgical wounds
Debridement for surgical wounds (2024) · Cochrane
no estimate extractedNRNo studies