Overall survival · high‐grade glioma
The review found no eligible studies for this question.
no estimate extracted
Studies not reported
No studies found
no estimate extracted
Studies not reported
No studies found
Progression‐free survival · high‐grade glioma
The review found no eligible studies for this question.
no estimate extracted
Studies not reported
No studies found
no estimate extracted
Studies not reported
No studies found
Quality of life · high‐grade glioma
The review found no eligible studies for this question.
no estimate extracted
Studies not reported
No studies found
no estimate extracted
Studies not reported
No studies found
Adverse events · high‐grade glioma
The review found no eligible studies for this question.
no estimate extracted
Studies not reported
No studies found
no estimate extracted
Studies not reported
No studies found
Overall survival · high‐grade glioma
The review found no eligible studies for this question.
no estimate extracted
Studies not reported
No studies found
no estimate extracted
Studies not reported
No studies found
Progression‐free survival · high‐grade glioma
The review found no eligible studies for this question.
no estimate extracted
Studies not reported
No studies found
no estimate extracted
Studies not reported
No studies found
Quality of life · high‐grade glioma
The review found no eligible studies for this question.
no estimate extracted
Studies not reported
No studies found
no estimate extracted
Studies not reported
No studies found
Adverse events · high‐grade glioma
The review found no eligible studies for this question.
no estimate extracted
Studies not reported
No studies found
no estimate extracted
Studies not reported
No studies found
Clinical pregnancy rate · women with polycystic ovary syndrome
It is very uncertain whether metformin changes clinical pregnancy rate per woman ‐ short protocol GnRH‐antagonist compared with placebo or no treatment (very low certainty).
Miscarriage · women with polycystic ovary syndrome
Metformin showed no clear difference in miscarriage rate per woman compared with placebo or no treatment (low certainty).
Reduction in anxiety symptoms (parent report) post‐treatment · children and adolescents with anxiety disorders
Reduction in anxiety symptoms (parent report) post‐treatment · children and adolescents with anxiety disorders
no estimate extracted
35 studies · 2137 participants
Low
no estimate extracted
30 studies · 1394 participants
Low
no estimate extracted
4 studies · 186 participants
Low
Gingivitis · Adults, 16 years and older (dentate)
It is very uncertain whether interdental brushing plus toothbrushing changes gingivitis (gingival index) compared with toothbrushing alone (very low certainty).
MD -0.53 [-0.83, -0.23]
1 study · 62 participants
Very low
MD -0.05 [-0.13, 0.03]
1 study · 31 participants
Very low
MD -0.53 [-0.83, -0.23]
1 study · 62 participants
Very low
Plaque · Adults, 16 years and older (dentate)
Interdental brushing plus toothbrushing may leads to lower plaque compared with toothbrushing alone (low certainty).
Gingivitis · Adults, 16 years and older (dentate)
Interdental brushing plus toothbrushing may leads to lower gingivitis (proportion of bleeding sites) compared with flossing plus toothbrushing (low certainty).
MD -0.06 [-0.08, -0.03]
6 studies · 234 participants
Low
SMD -0.40 [-0.70, -0.11]
3 studies · 183 participants
Low
SMD -0.53 [-0.81, -0.24]
7 studies · 326 participants
Low
Show 1 more finding
Plaque · Adults, 16 years and older (dentate)
It is very uncertain whether interdental brushing plus toothbrushing changes plaque compared with flossing plus toothbrushing (very low certainty).
SMD -0.47 [-0.84, -0.11]
5 studies · 290 participants
Very low
SMD 0.10 [-0.13, 0.33]
7 studies · 326 participants
Low
SMD -2.14 [-5.25, 0.97]
2 studies · 107 participants
Very low
Interproximal caries · Adults, 16 years and older (dentate)
The review found no eligible studies for this question.
Interproximal caries · Adults, 16 years and older (dentate)
The review found no eligible studies for this question.
Rate of weight gain (g/kg/day) · Parenterally fed preterm infants
Bronchopulmonary dysplasia/chronic lung disease · Parenterally fed preterm infants
Alternative lipid emulsion (LE) showed no clear difference in any BPD – OS‐LE vs S‐LE (sensitivity analysis) compared with soybean oil‐based LE (S‐LE) (low certainty).