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What do systematic reviews say?

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Evidence found and GRADE certainty

30 questions · 31 findings · 7 reviews · Headline outcomes only

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No studies found 3 · 9.7%GRADE not reported 0 · 0%Very low 6 · 19.4%Low 17 · 54.8%Moderate 5 · 16.1%High 0 · 0%

Very early cerebral revascularization vs delayed treatment

Perioperative death and strokes · people with recently symptomatic carotid artery stenosis

It is very uncertain whether very early cerebral revascularization changes stroke and Death < 30 days compared with delayed treatment (very low certainty).

2 findings from 1 review

Extended specialised early intervention (SEI) teams vs standard SEI teams plus treatment

Global state: recovery (assessed by symptom remission over a specified time period, as defined by study) · recent‐onset psychosis

It is very uncertain whether extended specialised early intervention (SEI) teams changes global state: recovery (assessed by symptom remission over a… compared with standard SEI teams plus treatment (very low certainty).

1 finding from 1 review

Surgery for Bell's palsy vs medical treatment (oral prednisolone) or no treatment

Complete recovery of facial nerve function at 12 months Defined as: complete recovery HB grade I. · Bell's palsy

It is very uncertain whether surgery for Bell's palsy changes complete recovery of facial nerve function at 12 months Defined as:… compared with medical treatment (oral prednisolone) or no treatment (very low certainty).

1 finding from 1 review

Prophylactic CPAP vs mechanical ventilation

Failed treatment defined as the need for mechanical ventilation · preterm infants

Prophylactic CPAP probably leads to lower failed treatment defined as the need for mechanical ventilation compared with mechanical ventilation (moderate certainty).

1 finding from 1 review