Findings

What do systematic reviews say?

181 questions · 190 findings · 14 reviews · Headline outcomes only

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No studies found 92 · 48.4%GRADE not reported 1 · 0.5%Very low 64 · 33.7%Low 25 · 13.2%Moderate 7 · 3.7%High 1 · 0.5%

Topical antibiotics vs placebo/no treatment

Serious complications · patients with mucopurulent otorrhoea

The review found no eligible studies for this question.

1 finding from 1 review

Topical antibiotics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topical antibiotics vs placebo/no treatment

Suspected ototoxicity · patients with mucopurulent otorrhoea

1 finding from 1 review

Topical antibiotics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 35 participants
Very low

Topical antibiotics vs acetic acid

Resolution of ear discharge ‐ measured at 1 to 2 weeks · chronic suppurative otitis media

It is very uncertain whether topical antibiotics changes resolution of ear discharge (1 to 2 weeks) Aminoglycosides compared with acetic acid (very low certainty).

1 finding from 1 review

Antibiotics versus topical antiseptics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
RR 0.88 [0.72, 1.08]
1 study · 100 participants
Very low

Topical antibiotics vs acetic acid

Resolution of ear discharge ‐ measured after 4 weeks · chronic suppurative otitis media

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotics versus topical antiseptics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topical antibiotics vs acetic acid

Quality of life ‐ not measured · chronic suppurative otitis media

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotics versus topical antiseptics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topical antibiotics vs acetic acid

Ear pain (otalgia) or discomfort or local irritation · chronic suppurative otitis media

It is very uncertain whether topical antibiotics changes ear pain, discomfort, irritation compared with acetic acid (very low certainty).

1 finding from 1 review

Antibiotics versus topical antiseptics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
RR 0.16 [0.02, 1.34]
2 studies · 189 participants
Very low

Topical antibiotics vs acetic acid

Hearing · chronic suppurative otitis media

1 finding from 1 review

Antibiotics versus topical antiseptics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 107 participants
Very low

Topical antibiotics vs acetic acid

Serious complications ‐ not measured · chronic suppurative otitis media

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotics versus topical antiseptics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topical antibiotics vs acetic acid

Suspected ototoxicity · chronic suppurative otitis media

It is very uncertain whether topical antibiotics changes suspected ototoxicity compared with acetic acid (very low certainty).

1 finding from 1 review

Antibiotics versus topical antiseptics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 100 participants
Very low

Topical antibiotics vs antiseptic agent

Number of wounds healed · people presenting for surgery where healing of surgical wound planned to be by primary intention

The review found no eligible studies for this question.

1 finding from 1 review

Topical antibiotics for preventing surgical site infection in wounds healing by primary intention 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topical antibiotics vs antiseptic agent

Surgical site infection · people presenting for surgery where healing of surgical wound planned to be by primary intention

Topical antibiotics probably leads to lower surgical site infection compared with antiseptic (moderate certainty).

1 finding from 1 review

Topical antibiotics for preventing surgical site infection in wounds healing by primary intention 2016 · Cochrane Headline outcomes only
RR 0.49 [0.3, 0.8]
4 studies · 1299 participants
Moderate

Topical antibiotics vs antiseptic agent

Allergic contact dermatitis · people presenting for surgery where healing of surgical wound planned to be by primary intention

It is very uncertain whether topical antibiotics changes allergic contact dermatitis compared with antiseptic (very low certainty).

1 finding from 1 review

Topical antibiotics for preventing surgical site infection in wounds healing by primary intention 2016 · Cochrane Headline outcomes only
RR 0.97 [0.52, 1.82]
1 study · 541 participants
Very low

Topical antibiotics vs antiseptic agent

Adverse event: anaphylaxis · people presenting for surgery where healing of surgical wound planned to be by primary intention

The review found no eligible studies for this question.

1 finding from 1 review

Topical antibiotics for preventing surgical site infection in wounds healing by primary intention 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topical antibiotics vs antiseptic agent

Antibiotic resistance · people presenting for surgery where healing of surgical wound planned to be by primary intention

The review found no eligible studies for this question.

1 finding from 1 review

Topical antibiotics for preventing surgical site infection in wounds healing by primary intention 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topical antibiotics vs another topical antibiotic or placebo

Risk of any ocular infection within 1 month following corneal abrasion · children and adults with corneal abrasion

1 finding from 1 review

Antibiotic prophylaxis for corneal abrasion 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Topical antibiotics vs another topical antibiotic or placebo

Time to clinical cure · children and adults with corneal abrasion

1 finding from 1 review

Antibiotic prophylaxis for corneal abrasion 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Topical antibiotics vs another topical antibiotic or placebo

Change in pain intensity from baseline to 1 month · children and adults with corneal abrasion

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotic prophylaxis for corneal abrasion 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topical antibiotics vs another topical antibiotic or placebo

Recurrent corneal erosion within 1 year · children and adults with corneal abrasion

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotic prophylaxis for corneal abrasion 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topical antibiotics vs another topical antibiotic or placebo

Visual acuity · children and adults with corneal abrasion

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotic prophylaxis for corneal abrasion 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topical antibiotics vs another topical antibiotic or placebo

Quality of life at 1 month · children and adults with corneal abrasion

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotic prophylaxis for corneal abrasion 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found