Quality of life · Adults (> 18 years) with a clinical diagnosis of periodontitis, receiving active (non-surgical anti-infective) treatment
The review found no eligible studies for this question.
1 finding from 1 review
Change in gingival recession (REC) · Adults (> 18 years) with a clinical diagnosis of periodontitis, receiving active (non-surgical anti-infective) treatment
It is very uncertain whether adjunctive antimicrobial photodynamic therapy (aPDT) applied after… changes change in gingival recession (REC) compared with subgingival instrumentation (SI) alone (hand or power-driven, or… (very low certainty).
2 findings from 1 review
Change in probing pocket depth (PPD) · Patients affected by infrabony defects requiring surgical treatment, regardless of their age or gender
It is very uncertain whether autologous platelet concentrates (APC) + open flap debridement (OFD) changes change in probing depth (PD) (mm) compared with OFD (open flap debridement) alone (very low certainty).
1 finding from 1 review
Tooth survival · Patients affected by infrabony defects requiring surgical treatment, regardless of their age or gender
1 finding from 1 review
Change in radiographic bone defect filling (RBF) (%) · Patients affected by infrabony defects requiring surgical treatment, regardless of their age or gender
Autologous platelet concentrates (APC) + open flap debridement (OFD)… led to higher change in radiographic bone defect filling (RBF) (%) compared with OFD + BG (open flap debridement + bone graft); GRADE not reported.
3 findings from 1 review
MD 9.99 [6.44, 13.55]
6 studies · 282 participants
GRADE not reported
MD 4.76 [1.27, 8.25]
6 studies · 162 participants
GRADE not reported
MD 8.10 [5.26, 10.94]
11 studies · 420 participants
Very low
Attachment change · Patients affected by infrabony defects requiring surgical treatment, regardless of their age or gender
It is very uncertain whether autologous platelet concentrates (APC) + guided tissue regeneration… changes change in clinical attachment level (CAL) (mm) compared with GTR (guided tissue regeneration) alone (very low certainty).
3 findings from 1 review
MD 0.42 [-0.02, 0.86]
7 studies · 248 participants
Very low
MD 0.27 [-0.39, 0.93]
5 studies · 164 participants
GRADE not reported
MD 0.54 [0.18, 0.89]
3 studies · 134 participants
GRADE not reported
Attachment change · Patients affected by infrabony defects requiring surgical treatment, regardless of their age or gender
It is very uncertain whether autologous platelet concentrates (APC) + enamel matrix derivative… changes change in clinical attachment level (CAL) (mm) compared with EMD (enamel matrix derivative) alone (very low certainty).
1 finding from 1 review
Pocket closure (complete pocket closure) · Patients affected by infrabony defects requiring surgical treatment, regardless of their age or gender
1 finding from 1 review
Attachment change · Patients affected by infrabony defects requiring surgical treatment, regardless of their age or gender
It is very uncertain whether autologous platelet concentrates (APC) + open flap debridement (OFD)… changes change in clinical attachment level (CAL) (mm) compared with OFD + BG (open flap debridement + bone graft) (very low certainty).
3 findings from 1 review
MD 0.72 [0.43, 1.00]
17 studies · 569 participants
Very low
MD 0.47 [0.11, 0.84]
11 studies · 272 participants
GRADE not reported
MD 0.84 [0.62, 1.06]
6 studies · 192 participants
GRADE not reported
Oral health-related quality of life · Patients affected by infrabony defects requiring surgical treatment, regardless of their age or gender
The review found no eligible studies for this question.
1 finding from 1 review
Tooth survival · Patients affected by infrabony defects requiring surgical treatment, regardless of their age or gender
1 finding from 1 review
Pocket closure (complete pocket closure) · Patients affected by infrabony defects requiring surgical treatment, regardless of their age or gender
1 finding from 1 review
Change in probing pocket depth (PPD) · Patients affected by infrabony defects requiring surgical treatment, regardless of their age or gender
It is very uncertain whether autologous platelet concentrates (APC) + open flap debridement (OFD)… changes change in probing depth (PD) (mm) compared with OFD + BG (open flap debridement + bone graft) (very low certainty).
3 findings from 1 review
MD 0.54 [0.33, 0.75]
17 studies · 569 participants
Very low
MD 0.62 [0.30, 0.94]
11 studies · 272 participants
GRADE not reported
MD 0.50 [0.31, 0.69]
10 studies · 381 participants
GRADE not reported
Pocket closure (complete pocket closure) · Patients affected by infrabony defects requiring surgical treatment, regardless of their age or gender
1 finding from 1 review
Tooth survival · Patients affected by infrabony defects requiring surgical treatment, regardless of their age or gender
1 finding from 1 review
Oral health-related quality of life · Patients affected by infrabony defects requiring surgical treatment, regardless of their age or gender
The review found no eligible studies for this question.
1 finding from 1 review
Change in probing pocket depth (PPD) · Patients affected by infrabony defects requiring surgical treatment, regardless of their age or gender
It is very uncertain whether autologous platelet concentrates (APC) + guided tissue regeneration… changes change in probing depth (PD) (mm) compared with GTR (guided tissue regeneration) alone (very low certainty).
3 findings from 1 review
MD 0.92 [-0.02, 1.86]
7 studies · 248 participants
Very low
MD 1.07 [-0.71, 2.86]
3 studies · 134 participants
GRADE not reported
MD 0.68 [-0.66, 2.02]
5 studies · 164 participants
GRADE not reported
Oral health-related quality of life · Patients affected by infrabony defects requiring surgical treatment, regardless of their age or gender
The review found no eligible studies for this question.
1 finding from 1 review
Change in probing pocket depth (PPD) · Patients affected by infrabony defects requiring surgical treatment, regardless of their age or gender
It is very uncertain whether autologous platelet concentrates (APC) + enamel matrix derivative… changes change in probing depth (PD) (mm) compared with EMD (enamel matrix derivative) alone (very low certainty).
1 finding from 1 review
Change in radiographic bone defect filling (RBF) (%) · Patients affected by infrabony defects requiring surgical treatment, regardless of their age or gender
It is very uncertain whether autologous platelet concentrates (APC) + enamel matrix derivative… changes change in radiographic bone defect filling (RBF) (%) compared with EMD (enamel matrix derivative) alone (very low certainty).
1 finding from 1 review