Autologous platelet concentrates (APC) + enamel matrix derivative (EMD) vs EMD (enamel matrix derivative) alone: Change in probing pocket depth (PPD)
- Population
- Patients affected by infrabony defects requiring surgical treatment, regardless of their age or gender
- Intervention
- Autologous platelet concentrates (APC) + enamel matrix derivative (EMD)
- Comparison
- EMD (enamel matrix derivative) alone
- Outcome
- Change in probing pocket depth (PPD)
It is very uncertain whether autologous platelet concentrates (APC) + enamel matrix derivative… changes change in probing depth (PD) (mm) compared with EMD (enamel matrix derivative) alone (very low certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Autologous platelet concentrates (APC) + enamel matrix derivative (EMD) vs EMD (enamel matrix derivative) alone Change in probing depth (PD) (mm) · Patients affected by infrabony defects requiring surgical treatment, regardless of their age or gender · All follow-ups It is very uncertain whether autologous platelet concentrates (APC) + enamel matrix derivative… changes change in probing depth (PD) (mm) compared with EMD (enamel matrix derivative) alone (very low certainty). Autologous platelet concentrates for treating periodontal infrabony defects (2018) · Cochrane All outcomes | MD 0.13 [-0.05, 0.30] | 2 studies · 75 participants | Very low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Autologous platelet concentrates for treating periodontal infrabony defects 2018 · Cochrane All outcomes | 27 February 2018 | Not listed | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.