Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

120 questions · 120 findings · 25 reviews · Anaesthesia

No studies found 17 · 14.2%GRADE not reported 6 · 5%Very low 23 · 19.2%Low 42 · 35%Moderate 29 · 24.2%High 3 · 2.5%

Intervention not reported

Any postoperative complication · adults aged 18 years or over undergoing general anaesthesia for non‐cardiac or non‐neurosurgical elective operations

The intervention probably leads to lower any postoperative complication (moderate certainty).

1 finding from 1 review

Low‐dose opioid based general anaesthesia vs high‐dose opioid based general anaesthesia

Mortality ‐ Death at any time after surgery · adult cardiac surgical patients

Low‐dose opioid‐based GA showed no clear difference in mortality ‐ Death at any time after surgery compared with high‐dose opioid‐based GA (low certainty).

1 finding from 1 review

Low‐dose opioid based general anaesthesia vs high‐dose opioid based general anaesthesia

Postoperative complications ‐ Myocardial infarction · adult cardiac surgical patients

Low‐dose opioid‐based GA showed no clear difference in postoperative myocardial infarction compared with high‐dose opioid‐based GA (low certainty).

1 finding from 1 review