Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

51 questions · 53 findings · 9 reviews · Headline outcomes only

No studies found 14 · 26.4%GRADE not reported 1 · 1.9%Very low 8 · 15.1%Low 18 · 34%Moderate 7 · 13.2%High 5 · 9.4%

Silver‐alginate dressing vs control

CRBSI ‐ Unit of analysis: infants Clinical and microbiological methods · newborn infants with central venous catheters

Silver‐alginate dressing showed no clear difference in CRBSI ‐ Unit of analysis: infants Clinical and microbiological methods compared with control (moderate certainty).

1 finding from 1 review

Silver‐alginate dressing vs control

CRBSI ‐ Unit of analysis: catheters Clinial and microbiological methods · newborn infants with central venous catheters

Silver‐alginate dressing showed no clear difference in CRBSI ‐ Unit of analysis: catheters Clinial and microbiological… compared with control (moderate certainty).

1 finding from 1 review

Intervention not reported

Silver versus nonadherent · people with venous leg ulcers

The intervention probably leads to higher silver versus nonadherent (moderate certainty).

1 finding from 1 review

Intervention not reported

Silver versus foam · people with venous leg ulcers

The intervention may leads to higher silver versus foam (low certainty).

1 finding from 1 review

Intervention not reported

Silver versus hydrocolloid · people with venous leg ulcers

The intervention may leads to higher silver versus hydrocolloid (low certainty).

1 finding from 1 review

Intervention not reported

Sucralfate versus silver · people with venous leg ulcers

It is very uncertain whether the intervention changes sucralfate versus silver (very low certainty).

1 finding from 1 review

Impregnated catheters vs antiseptic‐coated catheter

Symptomatic CAUTI: without microbiological evidence ‐ antibiotic versus silver alloy · Patients with an indwelling urethral catheter of short‐term duration

Antimicrobial‐impregnated catheter showed no clear difference in symptomatic CAUTI: without microbiological evidence ‐ antibiotic… compared with antiseptic‐coated catheter (moderate certainty).

1 finding from 1 review

Impregnated catheters vs antiseptic‐coated catheter

Symptomatic CAUTI: with microbiological evidence ‐ antibiotic versus silver alloy · Patients with an indwelling urethral catheter of short‐term duration

Antimicrobial‐impregnated catheter leads to lower symptomatic CAUTI: with microbiological evidence ‐ antibiotic versus… compared with antiseptic‐coated catheter (high certainty).

1 finding from 1 review

Antispetic‐coated catheter vs standard catheter

Patient discomfort whilst catheter is in situ · Patients with an indwelling urethral catheter of short‐term duration
2 findings from 1 review