Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

42 questions · 46 findings · 7 reviews

No studies found 8 · 17.4%GRADE not reported 2 · 4.3%Very low 2 · 4.3%Low 20 · 43.5%Moderate 11 · 23.9%High 3 · 6.5%

Sildenafil vs placebo

Global Efficacy Questionnaire (questions 1 & 2) (Questions assessing improvement attributed to medication compared to having no treatment at all) · people with antidepressant‐induced sexual dysfunction

Sildenafil probably leads to higher global Efficacy Questionnaire (questions 1 & 2) (Questions assessing… compared with placebo (moderate certainty).

1 finding from 1 review

Sildenafil vs placebo

Sexual function: Objective assessment (Global efficacy questionnaire, improved erections) · patients with sexual dysfunction due to antipsychotic drug therapy

ADJUNCTIVE TREATMENT ‐ SPECIFIC: SILDENAFIL may leads to higher sexual function: Objective assessment (Global efficacy… compared with PLACEBO (low certainty).

1 finding from 1 review

Sildenafil vs placebo

Leaving the study early · patients with sexual dysfunction due to antipsychotic drug therapy

It is very uncertain whether ADJUNCTIVE TREATMENT ‐ SPECIFIC: SILDENAFIL changes leaving the study early compared with PLACEBO (very low certainty).

1 finding from 1 review