Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

328 questions · 341 findings · 37 reviews · Gut

No studies found 55 · 16.1%GRADE not reported 4 · 1.2%Very low 137 · 40.2%Low 71 · 20.8%Moderate 56 · 16.4%High 18 · 5.3%

H. pylori eradication therapy vs control

Incidence of gastric cancer ‐ modified ITT analysis Histological examination · healthy asymptomatic H. pylori‐infected individuals

H. pylori eradication therapy probably leads to lower incidence of gastric cancer ‐ modified ITT analysisHistological… compared with control (moderate certainty).

1 finding from 1 review

Intervention not reported

Colonic transit rate (geometric centre of radioactive substance). Unit indicates position along with intestinal tract. Scale from: 1 (small intestine) to 5 (rectosigmoid area). · children with chronic constipation
1 finding from 1 review

Intervention not reported

Self‐perceived QoL (change from baseline) measured using Peds QL 4.0 Generic Core Scales, scoring 0‐100 points, higher score indicates better quality of life) · children with chronic constipation
1 finding from 1 review

Intervention not reported

Parent‐perceived QoL (change from baseline) measured using PedsQL 4.0 Generic Core Scales, scoring 0‐100 points, higher score indicates better quality of life) · children with chronic constipation
1 finding from 1 review