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Evidence found and GRADE certainty

171 questions · 174 findings · 15 reviews

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No studies found 48 · 27.6%GRADE not reported 13 · 7.5%Very low 61 · 35.1%Low 33 · 19%Moderate 15 · 8.6%High 4 · 2.3%

Fluoroquinolones vs amoxicillin

Response rate ‐ treatment failure · adults aged 18 years and above with diagnosis of non‐cystic fibrosis bronchiectasis

Fluoroquinolones may leads to lower response rate ‐ treatment failure compared with amoxicillin (low certainty).

1 finding from 1 review

Fluoroquinolones vs amoxicillin

Response rate ‐ microbiological response · adults aged 18 years and above with diagnosis of non‐cystic fibrosis bronchiectasis

Fluoroquinolones may leads to higher response rate ‐ microbiological response compared with amoxicillin (low certainty).

1 finding from 1 review

Fluoroquinolones vs amoxicillin

Response rate ‐ improvement in sputum purulence (excellent) · adults aged 18 years and above with diagnosis of non‐cystic fibrosis bronchiectasis

It is very uncertain whether fluoroquinolones changes response rate ‐ improvement in sputum purulence (excellent) compared with amoxicillin (very low certainty).

1 finding from 1 review

Fluoroquinolones vs beta‐lactams

Other adverse events clinical criteria · patients with Shigella dysentery

It is very uncertain whether fluoroquinolones changes other adverse events clinical criteria compared with beta‐lactams (very low certainty).

1 finding from 1 review

Fluoroquinolones vs macrolides

Other adverse events clinical criteria · patients with Shigella dysentery

It is very uncertain whether fluoroquinolones changes other adverse events clinical criteria compared with macrolides (very low certainty).

1 finding from 1 review

Fluoroquinolones vs beta‐lactams

Relapse · patients with Shigella dysentery

It is very uncertain whether fluoroquinolones changes relapse ‐ All trials clinical criteria compared with beta‐lactams (very low certainty).

1 finding from 1 review

Fluoroquinolones vs beta‐lactams

Serious adverse events clinical criteria · patients with Shigella dysentery

It is very uncertain whether fluoroquinolones changes serious adverse events clinical criteria compared with beta‐lactams (very low certainty).

1 finding from 1 review

Fluoroquinolones vs beta‐lactams

Discontinuation of medication due to adverse events · patients with Shigella dysentery

It is very uncertain whether fluoroquinolones changes adverse events leading to discontinuation of treatment compared with beta‐lactams (very low certainty).

1 finding from 1 review