Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

949 questions · 1,008 findings · 130 reviews · Gynaecology and Fertility

No studies found 195 · 19.3%GRADE not reported 30 · 3%Very low 346 · 34.3%Low 323 · 32%Moderate 101 · 10%High 13 · 1.3%

Analysis 7 ‐ Collagen membrane with polyethylene glycol and glycerol vs Ringer's lactate

Clinical pregnancy rate · patients with adhesion prevention after gynaecological surgery

It is very uncertain whether analysis 7 ‐ Collagen membrane with polyethylene glycol and glycerol changes clinical pregnancy rate compared with ringer's lactate (very low certainty).

1 finding from 1 review

Combined oral contraceptive pill vs no pretreatment

Live birth or ongoing pregnancy · women undergoing assisted reproduction

Combined oral contraceptive pill probably leads to lower live birth or ongoing pregnancy (COCP + Ant vs Ant) compared with no pretreatment (moderate certainty).

2 findings from 1 review

Summary of findings table ‐ Progestogens vs placebo or no pretreatment

Live birth or ongoing pregnancy · ovarian stimulation protocols for women undergoing ART

Progestogen showed no clear difference in live birth or ongoing pregnancy (Prog + Ant vs Ant) compared with placebo or no pretreatment (low certainty).

2 findings from 1 review

Summary of findings table ‐ Progestogens vs placebo or no pretreatment

Pregnancy loss · ovarian stimulation protocols for women undergoing ART

Progestogen showed no clear difference in pregnancy loss (Prog + Ag vs Ag) compared with placebo or no pretreatment (low certainty).

2 findings from 1 review

Summary of findings table ‐ Progestogens vs placebo or no pretreatment

Multiple pregnancy rate · ovarian stimulation protocols for women undergoing ART

The review found no eligible studies for this question.

2 findings from 1 review

Oestrogen vs no pretreatment

Live birth or ongoing pregnancy · ovarian stimulation protocols for women undergoing ART

Oestrogen showed no clear difference in live birth or ongoing pregnancy (Oestr + Ant vs Ant) compared with no pretreatment (moderate certainty).

2 findings from 1 review

Oestrogen vs no pretreatment

Pregnancy loss · ovarian stimulation protocols for women undergoing ART

It is very uncertain whether oestrogen changes pregnancy loss (Oestr + Ant vs Ant) compared with no pretreatment (very low certainty).

2 findings from 1 review

Oestrogen vs no pretreatment

Multiple pregnancy rate · ovarian stimulation protocols for women undergoing ART

The review found no eligible studies for this question.

2 findings from 1 review

Combined oral contraceptive pill vs no pretreatment

Pregnancy loss · women undergoing assisted reproduction

Combined oral contraceptive pill showed no clear difference in pregnancy loss (COCP + Ant vs Ant) compared with no pretreatment (moderate certainty).

2 findings from 1 review

Combined oral contraceptive pill vs no pretreatment

Multiple pregnancy rate · women undergoing assisted reproduction

Combined oral contraceptive pill showed no clear difference in multiple pregnancy rate (COCP + Ant vs Ant) compared with no pretreatment (low certainty).

2 findings from 1 review

Long protocol vs short protocol

Ongoing pregnancy / live birth rate per woman · women undergoing pituitary suppression in assisted reproduction

Long protocol showed no clear difference in live birth or ongoing pregnancies per woman randomised compared with short protocol (low certainty).

1 finding from 1 review

Long protocol continued GnRH agonist vs long protocol stop GnRH agonist

Clinical pregnancies Number of clinical pregnancies per woman randomised · women undergoing pituitary suppression in assisted reproduction

Long protocol continued GnRH agonist showed no clear difference in clinical pregnancies Number of clinical pregnancies per woman… compared with long protocol stop GnRH agonist (low certainty).

1 finding from 1 review