Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

57 questions · 57 findings · 11 reviews · Neonatal

No studies found 6 · 10.5%GRADE not reported 10 · 17.5%Very low 8 · 14%Low 15 · 26.3%Moderate 15 · 26.3%High 3 · 5.3%

Turning position vs supine under phototherapy

Rate of decline of serum bilirubin (micromol/L/hr) · term and preterm neonates with hyperbilirubinaemia

Turning position showed no clear difference in rate of fall of serum total bilirubin at 24 hours of starting… compared with supine under phototherapy (low certainty).

1 finding from 1 review

Sunlight (with or without filters or amplification) vs other sources of phototherapy

Use of conventional phototherapy, if sunlight (with or without filters or amplification) was first used for prevention or early treatmentc · infants with confirmed hyperbilirubinemia

The review found no eligible studies for this question.

1 finding from 1 review

Sunlight (with or without filters or amplification) vs other sources of phototherapy

Hyperthermia while receiving sunlight or conventional phototherapyg · infants with confirmed hyperbilirubinemia

Sunlight (with or without filters or amplification) probably leads to higher hyperthermia while receiving sunlight or conventional phototherapyg compared with other sources of phototherapy (moderate certainty).

1 finding from 1 review

Sunlight (with or without filters or amplification) vs other sources of phototherapy

Hypothermia while receiving sunlight or conventional phototherapyk · infants with confirmed hyperbilirubinemia

Sunlight (with or without filters or amplification) showed no clear difference in hypothermia while receiving sunlight or conventional phototherapyk compared with other sources of phototherapy (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ Transcutaneous bilirubin (TcB) screening vs visual assessment

Readmission for phototherapy for hyperbilirubinemia · newborns for hyperbilirubinemia

Summary of findings table ‐ Transcutaneous bilirubin (TcB) screening probably leads to lower readmission for phototherapy for hyperbilirubinemia compared with visual assessment (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ Transcutaneous bilirubin (TcB) screening vs visual assessment

Phototherapy before hospital discharge · newborns for hyperbilirubinemia

Summary of findings table ‐ Transcutaneous bilirubin (TcB) screening probably leads to higher phototherapy before hospital discharge compared with visual assessment (moderate certainty).

1 finding from 1 review

Sunlight (with or without filters or amplification) vs no treatment

Use of conventional phototherapy, if sunlight (with or without filters or amplification) was first used for prevention or early treatmentc · term and late preterm neonates

The review found no eligible studies for this question.

1 finding from 1 review

Prebiotic vs no prebiotics

Treatment with phototherapy · Neonates, including term neonates (gestational age ≥ 37 weeks), late preterm neonates (35 to 37 weeks' gestation) and preterm neonates (<…

Feeding supplementation with prebiotics may leads to lower treatment with phototherapy compared with no prebiotics (low certainty).

1 finding from 1 review