Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

73 questions · 73 findings · 9 reviews · Pain, Palliative and Supportive Care

No studies found 12 · 16.4%GRADE not reported 2 · 2.7%Very low 15 · 20.5%Low 26 · 35.6%Moderate 8 · 11%High 10 · 13.7%

SSRIs or SNRIs vs amitriptyline

Participants who withdraw because of an adverse event or any other reason · patients for whom migraine preventive interventions are indicated

SSRIs or SNRIs showed no clear difference in withdrawn (for any reasons and due to adverse events) compared with amitriptyline (low certainty).

1 finding from 1 review