Eradication of MRSA · adults and children with cystic fibrosis and a positive microbiological isolate of MRSA from a respiratory tract specimen
Oral plus nebulised antibiotics showed no clear difference in eradication of MRSA compared with oral antibiotics plus nebulised placebo (low certainty).
1 finding from 1 review
Time until next positive MRSA isolate (from clinically relevant respiratory culture) · adults and children with cystic fibrosis and a positive microbiological isolate of MRSA from a respiratory tract specimen
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Need for antibiotics days of antibiotic use · children with cystic fibrosis
It is very uncertain whether summary of findings: Zinc supplementation changes need for antibiotics number of days on IV or oral antibiotics compared with placebo (very low certainty).
1 finding from 1 review
Healing of osteonecrosis - improvement ('healed' or 'improved' vs 'unchanged' or 'worse') · People with BRONJ (mean age ~66 years; most treated with bisphosphonates for cancer (multiple myeloma, breast cancer) or osteoporosis)
Hyperbaric oxygen therapy plus standard care (surgery, antibiotics,… showed no clear difference in healing of osteonecrosis - improvement ('healed' or 'improved' vs… compared with standard care alone (surgery, antibiotics, oral rinse); GRADE not reported.
5 findings from 1 review
RR 1.75 [0.51, 5.98]
1 study · 18 participants
GRADE not reported
RR 1.78 [0.97, 3.28]
1 study · 46 participants
GRADE not reported
RR 1.94 [1.01, 3.74]
1 study · 45 participants
Very low
Show 2 more findings
Healing of osteonecrosis - healed ('healed' vs 'improved', 'unchanged' or 'worse') · People with BRONJ (mean age ~66 years; most treated with bisphosphonates for cancer (multiple myeloma, breast cancer) or osteoporosis)
Hyperbaric oxygen therapy plus standard care (surgery, antibiotics,… showed no clear difference in healing of osteonecrosis - healed ('healed' vs 'improved',… compared with standard care alone (surgery, antibiotics, oral rinse); GRADE not reported.
5 findings from 1 review
RR 1.56 [0.77, 3.18]
1 study · 46 participants
GRADE not reported
RR 1.00 [0.25, 4.00]
1 study · 18 participants
GRADE not reported
RR 0.95 [0.44, 2.04]
1 study · 40 participants
GRADE not reported
Show 2 more findings
Pain · People with BRONJ (mean age ~66 years; most treated with bisphosphonates for cancer (multiple myeloma, breast cancer) or osteoporosis)
1 finding from 1 review
Adverse effects · People with BRONJ (mean age ~66 years; most treated with bisphosphonates for cancer (multiple myeloma, breast cancer) or osteoporosis)
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
0 studies
No studies found
Quality of life · People with BRONJ (mean age ~66 years; most treated with bisphosphonates for cancer (multiple myeloma, breast cancer) or osteoporosis)
1 finding from 1 review
Fever clearance time · children with acute pyelonephritis
1 finding from 1 review
Renal parenchymal damage at 6 to 12 months: all included children with acute pyelonephritis DMSA scans · children with acute pyelonephritis
Oral showed no clear difference in renal parenchymal damage at 6 to 12 months: all included children… compared with IV followed by oral (11 days) therapy (moderate certainty).
1 finding from 1 review
Renal parenchymal damage at 6 to 12 months: children with renal parenchymal damage on initial DMSA · children with acute pyelonephritis
Oral showed no clear difference in renal parenchymal damage at 6 to 12 months: children with renal… compared with IV followed by oral (11 days) therapy (moderate certainty).
1 finding from 1 review
Active trachoma · people (any age) with active trachoma
Oral showed no clear difference in active trachoma Clinical assessment: active trachoma defined as TF,… compared with topical antibiotic (low certainty).
1 finding from 1 review
Ocular chlamydia trachomatis infection · people (any age) with active trachoma
1 finding from 1 review
Antibiotic resistance · people (any age) with active trachoma
The review found no eligible studies for this question.
1 finding from 1 review
Antibiotics for trachoma 2019 · Cochrane Headline outcomes only no estimate extracted
Studies not reported
No studies found
Adverse effects · people (any age) with active trachoma
1 finding from 1 review
Adverse effects of antibiotics: leading to trial discontinuation · adults and children with cystic fibrosis and a positive microbiological isolate of P aeruginosa from a respiratory tract specimen
1 finding from 1 review
Number experiencing adverse effects · children with cystic fibrosis and a new culture positive for P aeruginosa
Inhaled tobramycin (TNS) plus oral azithromycin showed no clear difference in adverse effects of antibiotics: number of participants experiencing… compared with TNS plus oral placebo (moderate certainty).
1 finding from 1 review
Need for additional antibiotics: participants needing extra IV antibiotics · adults and children with cystic fibrosis
1 finding from 1 review
Peritonitis · chronic peritoneal dialysis patients
Oral or topical or intraperitoneal antibiotics showed no clear difference in peritonitis (number of patients with one or more episodes) compared with placebo/no treatment (low certainty).
1 finding from 1 review
Exit‐site/tunnel infection · chronic peritoneal dialysis patients
Oral or topical or intraperitoneal antibiotics showed no clear difference in exit‐site/tunnel infection (number of patients with one or more… compared with placebo/no treatment (low certainty).
1 finding from 1 review