Question · asked by 1 review

Oral azithromycin vs placebo: Need for additional antibiotics: participants needing extra IV antibiotics

Population
adults and children with cystic fibrosis
Intervention
Oral azithromycin
Comparison
placebo
Outcome
Need for additional antibiotics: participants needing extra IV antibiotics

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Summary of findings ‐ oral azithromycin vs placebo
Need for additional antibiotics: participants needing extra IV antibiotics · adults and children with cystic fibrosis
Macrolide antibiotics (including azithromycin) for cystic fibrosis (2024) · Cochrane Headline outcomes only
no estimate extracted3 studies · 527 participantsHigh

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Macrolide antibiotics (including azithromycin) for cystic fibrosis
2024 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.