Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

929 questions · 946 findings · 295 reviews · Headline outcomes only

No studies found 150 · 15.9%GRADE not reported 47 · 5%Very low 312 · 33%Low 262 · 27.7%Moderate 138 · 14.6%High 37 · 3.9%

Twice daily or more vs once daily topical corticosteroid

Patient‐reported symptoms of eczema · children and adults, most with moderate to severe eczema

Twice daily or more showed no clear difference in patient‐reported symptoms of eczema: PGA (number with cleared or… compared with once daily topical corticosteroid (low certainty).

1 finding from 1 review

More than 24 hours of antibiotics vs 24 hours of antibiotics

Abdominal surgical site infection · people undergoing laparotomy for penetrating abdominal trauma

It is very uncertain whether more than 24 hours of antibiotics changes abdominal surgical site infection compared with 24 hours of antibiotics (very low certainty).

1 finding from 1 review

More than 24 hours of antibiotics vs 24 hours of antibiotics

All‐cause mortality · people undergoing laparotomy for penetrating abdominal trauma

It is very uncertain whether more than 24 hours of antibiotics changes mortality compared with 24 hours of antibiotics (very low certainty).

1 finding from 1 review

More than 24 hours of antibiotics vs 24 hours of antibiotics

Intra‐abdominal infection · people undergoing laparotomy for penetrating abdominal trauma

It is very uncertain whether more than 24 hours of antibiotics changes intra‐abdominal infection compared with 24 hours of antibiotics (very low certainty).

1 finding from 1 review