Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

133 questions · 145 findings · 28 reviews · Gut

No studies found 12 · 8.3%GRADE not reported 5 · 3.4%Very low 64 · 44.1%Low 43 · 29.7%Moderate 20 · 13.8%High 1 · 0.7%

Metronidazole vs vancomycin

Cure (combined symptomatic and bacteriologic cure) ‐ mild disease · patients with Clostridium difficile‐associated diarrhoea in adults

It is very uncertain whether metronidazole changes cure (combined symptomatic and bacteriologic cure) ‐ mild disease compared with vancomycin (very low certainty).

1 finding from 1 review

Metronidazole vs vancomycin

Cure (combined symptomatic and bacteriologic cure) ‐ severe disease · patients with Clostridium difficile‐associated diarrhoea in adults

It is very uncertain whether metronidazole changes cure (combined symptomatic and bacteriologic cure) ‐ severe disease compared with vancomycin (very low certainty).

1 finding from 1 review

Summary of findings table (sensitivity analysis): interventions esophageal and GE‐junction carcinoma vs gastric carcinoma

Sensitivity analysis, meta‐regression analysis, first part · palliative participants with esophageal and GE‐junction carcinoma or gastric carcinoma

It is very uncertain whether summary of findings table (sensitivity analysis): interventions… changes sensitivity analysis, meta‐regression analysis, first part compared with gastric carcinoma (very low certainty).

1 finding from 1 review