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Evidence found and GRADE certainty

231 questions · 231 findings · 28 reviews · Anaesthesia

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No studies found 41 · 17.7%GRADE not reported 10 · 4.3%Very low 35 · 15.2%Low 94 · 40.7%Moderate 35 · 15.2%High 16 · 6.9%

rHuEPO with iron vs control treatment with or without iron

Subgroup Hb concentration immediately prior to surgery (g/dL) rHuEPO low (150 to 300 IU/kg BW) · adult participants, irrespective of gender and type of non‐cardiac surgery, with mild or severe preoperative anaemia
1 finding from 1 review

4% prilocaine plain vs 2% lidocaine, 1:100,000 epinephrine

Adverse effects: paraesthesia following injection · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario studies in which…

The review found no eligible studies for this question.

1 finding from 1 review
  • Injectable local anaesthetic agents for dental anaesthesia 2018 · Cochrane All outcomes
    SoF: See comment; 0 participants (0 studies); 1 case of prolonged anaesthesia recorded; no clinical studies met the outcome definition (unable to confirm whether prolonged anaesthesia = paraesthesia).
    0 studies
    No studies found

4% articaine, 1:100,000 epinephrine vs 2% lidocaine, 1:100,000 epinephrine

Adverse effects: pain following injection · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario studies in which…

4% articaine, 1:100,000 epinephrine probably leads to higher adverse effects: pain following injection, Heft-Parker VAS 0-170 mm compared with 2% lidocaine, 1:100,000 epinephrine (moderate certainty).

1 finding from 1 review

4% articaine, 1:200,000 epinephrine vs 4% articaine, 1:100,000 epinephrine

Adverse effects: pain following injection · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario studies in which…
1 finding from 1 review

Intervention not reported

Difficult tracheal intubation: low risk of bias trials · improving conditions during tracheal intubation or direct laryngoscopy in adults and adolescents

The intervention probably leads to higher difficult tracheal intubation: low risk of bias trials (moderate certainty).

1 finding from 1 review

Intervention not reported

One or more events of upper airway discomfort or injury: low risk of bias trials · improving conditions during tracheal intubation or direct laryngoscopy in adults and adolescents

The intervention led to higher one or more events of upper airway discomfort or injury: low risk of…; GRADE not reported.

1 finding from 1 review