Cochrane · systematic review · CD009237

Avoidance versus use of neuromuscular blocking agents for improving conditions during tracheal intubation or direct laryngoscopy in adults and adolescents

Lundstrøm, LH, Duez, CHV, Nørskov, AK, et al. · Cochrane Database of Systematic Reviews · 2017 · Cochrane Library

AnaesthesiaAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
9
current version
GRADE rated
4
No studies
2
Included studies
NR
No studies 2 · 22.2%Ungraded 3 · 33.3%Very low 0 · 0%Low 2 · 22.2%Moderate 2 · 22.2%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Summary of findings table: primary and secondary outcomes

Population: improving conditions during tracheal intubation or direct laryngoscopy in adults and adolescents
9 questions
OutcomeEffectEvidenceStatus / GRADE
Primary outcomes
no estimate extractedNRNo studies
Difficult tracheal intubation: low risk of bias trials
RR 13.27 [8.19, 21.49]4 studies · 508 participantsModerate
Downgraded: indirectness
Difficult tracheal intubation: all trials
RR 5 [3.49, 7.15]34 studies · 3565 participantsLow
Downgraded: risk of bias, imprecision, inconsistency, indirectness
One or more events of upper airway discomfort or injury: low risk of bias trials
RR 2.74 [1.21, 6.21]1 study · 73 participantsUngraded
One or more events of upper airway discomfort or injury: all trials
RR 1.37 [1.09, 1.74]7 studies · 846 participantsModerate
Downgraded: risk of bias, imprecision, inconsistency, indirectness
Mortality
no estimate extracted0 studies · 34 participantsUngraded
Secondary outcomes
no estimate extractedNRNo studies
Difficult laryngoscopy: low risk of bias trials
RR 4 [0.47, 34.2]1 study · 78 participantsUngraded
Difficult laryngoscopy: all trials
RR 2.54 [1.53, 4.21]13 studies · 1308 participantsLow
Downgraded: risk of bias, imprecision, inconsistency, indirectness