Local anaesthetic vs placebo or no treatment
Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · women undergoing outpatient hysteroscopy
1 finding from 1 review
- no estimate extracted10 studies · 1496 participantsLow
Findings
What do systematic reviews say?
339 questions · 355 findings · 25 reviews
No studies found 134 · 37.7%GRADE not reported 38 · 10.7%Very low 87 · 24.5%Low 66 · 18.6%Moderate 27 · 7.6%High 3 · 0.8%
Local anaesthetic vs placebo or no treatment
Pain score within 30 min of procedure · women undergoing outpatient hysteroscopy
1 finding from 1 review
- no estimate extracted5 studies · 545 participantsLow
Local anaesthetic vs placebo or no treatment
Pain score more than 30 min after procedure · women undergoing outpatient hysteroscopy
1 finding from 1 review
- no estimate extracted4 studies · 450 participantsLow
Local anaesthetic vs placebo or no treatment
Vasovagal reaction · women undergoing outpatient hysteroscopy
It is very uncertain whether local anaesthetic changes vasovagal reaction compared with placebo or no treatment (very low certainty).
1 finding from 1 review
- OR 0.7 [0.43, 1.13]8 studies · 1309 participantsVery low
Local anaesthetic vs placebo or no treatment
Non pelvic pain · women undergoing outpatient hysteroscopy
It is very uncertain whether local anaesthetic changes non‐pelvic pain compared with placebo or no treatment (very low certainty).
1 finding from 1 review
- OR 1.76 [0.53, 5.8]1 study · 99 participantsVery low
Summary of findings: ultrasound‐guided injection of corticosteroid and local anaesthetic (UG CS+LA) vs injection with corticosteroid and anaesthetic
Adverse events · Morton's neuroma
Summary of findings: ultrasound‐guided injection of corticosteroid… showed no clear difference in adverse events compared with non‐ultrasound‐guided injection of corticosteroid and local… (low certainty).
1 finding from 1 review
- RR 0.42 [0.12, 1.39]2 studies · 116 participantsLow
Summary of findings: ultrasound‐guided injection of corticosteroid and local anaesthetic (UG CS+LA) vs injection with corticosteroid and anaesthetic
Pain at short term (4 weeks) VAS 10‐cm scale, which was translated to a 0 to 100 scale in which lower scores mean less pain. · Morton's neuroma
1 finding from 1 review
- no estimate extracted2 studies · 116 participantsModerate
Summary of findings: ultrasound‐guided injection of corticosteroid and local anaesthetic (UG CS+LA) vs injection with corticosteroid and anaesthetic
Function: · Morton's neuroma
1 finding from 1 review
- no estimate extracted2 studies · 116 participantsModerate
Summary of findings: ultrasound‐guided injection of corticosteroid and local anaesthetic (UG CS+LA) vs injection with corticosteroid and anaesthetic
Health‐related quality of life · Morton's neuroma
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Summary of findings: ultrasound‐guided injection of corticosteroid and local anaesthetic (UG CS+LA) vs injection with corticosteroid and anaesthetic
Satisfaction: 4‐item Likert scale (dichotomised into satisfied and dissatisfied) · Morton's neuroma
Summary of findings: ultrasound‐guided injection of corticosteroid… may leads to higher satisfaction: 4‐point Likert scale (dichotomised into satisfied and… compared with non‐ultrasound‐guided injection of corticosteroid and local… (low certainty).
1 finding from 1 review
- RR 1.71 [1.19, 2.44]2 studies · 114 participantsLow
0.5% bupivacaine, 1:200,000 epinephrine vs 2% lidocaine, 1:100,000 epinephrine
Adverse effects: allergy to local anaesthetic · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario studies in which…
The review found no eligible studies for this question.
1 finding from 1 review
- SoF: Not measured.0 studiesNo studies found
4% articaine, 1:100,000 epinephrine vs 2% mepivacaine, 1:100,000 epinephrine
Adverse effects: allergy to local anaesthetic · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario studies in which…
The review found no eligible studies for this question.
1 finding from 1 review
- SoF: Not measured.0 studiesNo studies found
4% prilocaine plain vs 2% lidocaine, 1:100,000 epinephrine
Adverse effects: allergy to local anaesthetic · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario studies in which…
The review found no eligible studies for this question.
1 finding from 1 review
- SoF: Not measured.0 studiesNo studies found
3% prilocaine, 0.03 IU felypressin vs 2% lidocaine, 1:100,000 epinephrine
Adverse effects: allergy to local anaesthetic · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario studies in which…
The review found no eligible studies for this question.
1 finding from 1 review
- SoF: Not measured.0 studiesNo studies found
4% articaine, 1:100,000 epinephrine vs 2% lidocaine, 1:100,000 epinephrine
Adverse effects: allergy to local anaesthetic · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario studies in which…
The review found no eligible studies for this question.
1 finding from 1 review
- SoF: Not measured.0 studiesNo studies found
4% articaine, 1:200,000 epinephrine vs 0.5% bupivacaine, 1:200,000 epinephrine
Adverse effects: allergy to local anaesthetic · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario studies in which…
The review found no eligible studies for this question.
1 finding from 1 review
- SoF: Not measured.0 studiesNo studies found
4% articaine, 1:200,000 epinephrine vs 4% articaine, 1:100,000 epinephrine
Adverse effects: allergy to local anaesthetic · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario studies in which…
1 finding from 1 review
- SoF: See comment, not estimable; 63 participants, 187 interventions (1 study); 1 case of urticaria occurred (unclear which anaesthetic). Not pooled/graded.1 study · 63 participantsGRADE not reported
2% mepivacaine, 1:100,000 epinephrine vs 2% lidocaine, 1:100,000 epinephrine
Adverse effects: allergy to local anaesthetic · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario studies in which…
The review found no eligible studies for this question.
1 finding from 1 review
- SoF: Not measured.0 studiesNo studies found
Continuous local anaesthetic wound infusion vs placebo
Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · adults undergoing elective midline laparotomy for colorectal resection
1 finding from 1 review
- Continuous local anaesthetic wound infusion for postoperative pain after midline laparotomy for colorectal resection… 2019 · Cochrane Headline outcomes onlyno estimate extracted5 studies · 511 participantsHigh
Continuous local anaesthetic wound infusion vs placebo
Pain (VAS scores) on movement at postoperative day 1 Scale from: 0 to 10. · adults undergoing elective midline laparotomy for colorectal resection
1 finding from 1 review
- Continuous local anaesthetic wound infusion for postoperative pain after midline laparotomy for colorectal resection… 2019 · Cochrane Headline outcomes onlyno estimate extracted3 studies · 407 participantsLow