Diagnostic accuracy for proximal caries detection (dentin detection level) · Patients with permanent posterior teeth, proximal surfaces assessed clinically (in vivo)
Under in vivo conditions, laser fluorescence (DIAGNOdent 2190) had a pooled specificity of 0.60 (95% CI 0.15, 0.93) for proximal caries detection at the dentin detection level; ungraded.
4 findings from 1 review
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Diagnostic accuracy for proximal caries detection (caries detection level) · Patients with permanent posterior teeth, proximal surfaces assessed clinically (in vivo)
Under in vivo conditions, laser fluorescence (DIAGNOdent 2190) had a summary ROC AUC of 0.96 for proximal caries detection at the caries detection level; ungraded.
4 findings from 1 review
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Diagnostic accuracy for proximal caries detection (caries detection level) · Extracted permanent posterior teeth with proximal surfaces (in vitro)
Under in vitro conditions, laser fluorescence (DIAGNOdent 2190) had a summary ROC AUC of 0.91 for proximal caries detection at the caries detection level; ungraded.
4 findings from 1 review
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Diagnostic accuracy for occlusal caries detection at the dentin caries detection level (D0-2 versus D3-4) · Extracted human permanent posterior teeth (premolars and molars), occlusal (pit-and-fissure) surfaces
In in vitro, laser fluorescence pen (2190) pooled specificity was 0.77 (95% CI 0.62 to 0.88) for occlusal caries at the dentin detection level; ungraded.
4 findings from 1 review
Specificity 0.77 [0.62, 0.88]
4 studies
GRADE not reported
Sensitivity 0.63 [0.37, 0.83]
4 studies
GRADE not reported
DOR 5.85 [1.77, 19.30]
4 studies
GRADE not reported
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AUC 0.78
4 studies
GRADE not reported
Diagnostic accuracy for occlusal caries detection at the caries detection level (D0 versus D1-D4) · Extracted human permanent posterior teeth (premolars and molars), occlusal (pit-and-fissure) surfaces
In in vitro, laser fluorescence pen (2190) pooled sensitivity was 0.78 (95% CI 0.44 to 0.94) for occlusal caries at the caries detection level; ungraded.
4 findings from 1 review
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Specificity · Adults presenting asymptomatically or suspected of having root caries (in vivo studies); extracted teeth of adults (in vitro studies). 2…
1 finding from 1 review
Sensitivity · Adults presenting asymptomatically or suspected of having root caries (in vivo studies); extracted teeth of adults (in vitro studies). 2…
1 finding from 1 review
Caries lesion initiation/progression (ICDAS score, laser fluorescence/DIAGNOdent, photographic pixels, enamel acid resistance) · Patients (children and adults, age 3-40 years) with initial enamel caries lesions (non-orthodontic and orthodontic)
No meta-analysis was possible for the 5 in vivo RCTs (high heterogeneity); narratively nHA showed generally no significant difference versus fluoridated dentifrice, and the evidence was not graded (ungraded).
1 finding from 1 review
Efficacy of nano-hydroxyapatite on caries prevention-a systematic review and meta-analysis. 2022 All outcomesMedian follow-up 6 months (range 6-12 months) · In vivo (clinical); non-orthodontic and orthodontic patients
No meta-analysis was performed for the in vivo studies owing to high heterogeneity (population, control group, outcomes, follow-up periods, risk of bias) and differing statistical designs (e.g., non-inferiority);…
5 studies · 420 participants
GRADE not reported
White spot lesions assessed by laser fluorescence (DIAGNOdent) · Patients of any age (11-40 years) receiving comprehensive/fixed orthodontic treatment with fixed appliances
White spot lesions were also measured by laser fluorescence in 3 sealant-vs-no-sealant studies, but no meta-analysis was possible due to incompatible reporting.
1 finding from 1 review
White spot lesions assessed by laser fluorescence (DIAGNOdent) · Patients of any age (11-40 years) receiving comprehensive/fixed orthodontic treatment with fixed appliances
White spot lesions were also measured by laser fluorescence in 3 fluoride-vs-non-fluoride studies, but no meta-analysis was possible due to incompatible reporting.
1 finding from 1 review