Laser fluorescence (DIAGNOdent 2190/pen) vs Histological validation (serial sectioning, grinding, hemisection, or microradiography): Diagnostic accuracy for occlusal caries detection at the caries detection level (D0 versus D1-D4)
In in vitro, laser fluorescence pen (2190) pooled sensitivity was 0.78 (95% CI 0.44 to 0.94) for occlusal caries at the caries detection level; ungraded.
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Laser fluorescence pen (DIAGNOdent 2190/Pen) vs Histological validation (serial sectioning, grinding, hemisection, or microradiography) Diagnostic accuracy for occlusal caries detection at the caries detection level (D0 versus D1-D4) · Extracted human permanent posterior teeth (premolars and molars), occlusal (pit-and-fissure) surfaces · in vitro In in vitro, laser fluorescence pen (2190) pooled sensitivity was 0.78 (95% CI 0.44 to 0.94) for occlusal caries at the caries detection level; ungraded. Systematic review and meta-analysis of diagnostic methods for occlusal surface caries. (2021) All outcomes | Sensitivity 0.78 [0.44, 0.94] | 2 studies | GRADE not reported |
Laser fluorescence pen (DIAGNOdent 2190/Pen) vs Histological validation (serial sectioning, grinding, hemisection, or microradiography) Diagnostic accuracy for occlusal caries detection at the caries detection level (D0 versus D1-D4) · Extracted human permanent posterior teeth (premolars and molars), occlusal (pit-and-fissure) surfaces · in vitro In in vitro, laser fluorescence pen (2190) pooled summary ROC AUC was 0.77 for occlusal caries at the caries detection level; ungraded. Systematic review and meta-analysis of diagnostic methods for occlusal surface caries. (2021) All outcomes | AUC 0.77 | 2 studies | GRADE not reported |
Laser fluorescence pen (DIAGNOdent 2190/Pen) vs Histological validation (serial sectioning, grinding, hemisection, or microradiography) Diagnostic accuracy for occlusal caries detection at the caries detection level (D0 versus D1-D4) · Extracted human permanent posterior teeth (premolars and molars), occlusal (pit-and-fissure) surfaces · in vitro In in vitro, laser fluorescence pen (2190) pooled diagnostic odds ratio was 11.83 (95% CI 2.66 to 52.63) for occlusal caries at the caries detection level; ungraded. Systematic review and meta-analysis of diagnostic methods for occlusal surface caries. (2021) All outcomes | DOR 11.83 [2.66, 52.63] | 2 studies | GRADE not reported |
Laser fluorescence pen (DIAGNOdent 2190/Pen) vs Histological validation (serial sectioning, grinding, hemisection, or microradiography) Diagnostic accuracy for occlusal caries detection at the caries detection level (D0 versus D1-D4) · Extracted human permanent posterior teeth (premolars and molars), occlusal (pit-and-fissure) surfaces · in vitro In in vitro, laser fluorescence pen (2190) pooled specificity was 0.77 (95% CI 0.62 to 0.87) for occlusal caries at the caries detection level; ungraded. Systematic review and meta-analysis of diagnostic methods for occlusal surface caries. (2021) All outcomes | Specificity 0.77 [0.62, 0.87] | 2 studies | GRADE not reported |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Systematic review and meta-analysis of diagnostic methods for occlusal surface caries. 2021 All outcomes | 31 December 2018 | 73 | Not applicable |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.