What do systematic reviews say?

Summary of findings table ‐ Intraperitoneal local anaesthetic vs control

• Intraperitoneal local anaesthetic instillation versus no intraperitoneal local anaesthetic instillation for… 2021 · Cochrane Headline outcomes only
  no estimate extracted
  12 studies · 936 participants
  Moderate

Summary of findings table ‐ Intraperitoneal local anaesthetic vs control

It is very uncertain whether summary of findings table ‐ Intraperitoneal local anaesthetic changes proportion discharged as day surgery compared with control (very low certainty).

• Intraperitoneal local anaesthetic instillation versus no intraperitoneal local anaesthetic instillation for… 2021 · Cochrane Headline outcomes only
  RR 1.43 [0.64, 3.2]
  3 studies · 242 participants
  Very low

Summary of findings table ‐ Intraperitoneal local anaesthetic vs control

• Intraperitoneal local anaesthetic instillation versus no intraperitoneal local anaesthetic instillation for… 2021 · Cochrane Headline outcomes only
  no estimate extracted
  57 studies · 4046 participants
  Low

Summary of findings table ‐ Intraperitoneal local anaesthetic vs control

• Intraperitoneal local anaesthetic instillation versus no intraperitoneal local anaesthetic instillation for… 2021 · Cochrane Headline outcomes only
  no estimate extracted
  52 studies · 3588 participants
  Low

Intraperitoneal lidocaine instillation vs IM morphine

• Interventions for intra‐operative pain relief during postpartum mini‐laparotomy tubal ligation 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  Very low

Intraperitoneal lidocaine instillation vs IM morphine

Intraperitoneal lidocaine instillation may leads to lower number of women requiring rescue medication compared with intramuscular morphine (low certainty).

• Interventions for intra‐operative pain relief during postpartum mini‐laparotomy tubal ligation 2019 · Cochrane Headline outcomes only
  RR 0.22 [0.09, 0.54]
  Studies not reported
  Low

Oral or topical or intraperitoneal antibiotics vs placebo/no treatment

Oral or topical or intraperitoneal antibiotics showed no clear difference in peritonitis (number of patients with one or more episodes) compared with placebo/no treatment (low certainty).

• Antimicrobial agents for preventing peritonitis in peritoneal dialysis patients 2017 · Cochrane Headline outcomes only
  RR 0.82 [0.57, 1.19]
  5 studies · 395 participants
  Low

Oral or topical or intraperitoneal antibiotics vs placebo/no treatment

Oral or topical or intraperitoneal antibiotics showed no clear difference in exit‐site/tunnel infection (number of patients with one or more… compared with placebo/no treatment (low certainty).

• Antimicrobial agents for preventing peritonitis in peritoneal dialysis patients 2017 · Cochrane Headline outcomes only
  RR 0.45 [0.19, 1.04]
  3 studies · 191 participants
  Low

Oral or topical or intraperitoneal antibiotics vs placebo/no treatment

Oral or topical or intraperitoneal antibiotics showed no clear difference in catheter removal or replacement (number of patients) compared with placebo/no treatment (low certainty).

• Antimicrobial agents for preventing peritonitis in peritoneal dialysis patients 2017 · Cochrane Headline outcomes only
  RR 0.82 [0.46, 1.46]
  5 studies · 395 participants
  Low

Subdiaphragmatic intraperitoneal local anaesthetic vs control

Subdiaphragmatic intraperitoneal local anaesthetic showed no clear difference in incidence of STP at 24 hours post‐operatively compared with control (moderate certainty).

• Interventions to reduce shoulder pain following gynaecological laparoscopic procedures 2019 · Cochrane Headline outcomes only
  OR 0.72 [0.42, 1.23]
  4 studies · 336 participants
  Moderate

Subdiaphragmatic intraperitoneal local anaesthetic vs control

• Interventions to reduce shoulder pain following gynaecological laparoscopic procedures 2019 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 50 participants
  Low

Subdiaphragmatic intraperitoneal local anaesthetic vs control

• Interventions to reduce shoulder pain following gynaecological laparoscopic procedures 2019 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 165 participants
  GRADE not reported

Subdiaphragmatic intraperitoneal local anaesthetic vs control

• Interventions to reduce shoulder pain following gynaecological laparoscopic procedures 2019 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 129 participants
  Low

Abdominal paracentesis and intraperitoneal infusion of catumaxomab vs abdominal paracentesis alone

• Management of drainage for malignant ascites in gynaecological cancer 2019 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 245 participants
  Very low

Abdominal paracentesis and intraperitoneal infusion of catumaxomab vs abdominal paracentesis alone

The review found no eligible studies for this question.

• Management of drainage for malignant ascites in gynaecological cancer 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Abdominal paracentesis and intraperitoneal infusion of catumaxomab vs abdominal paracentesis alone

• Management of drainage for malignant ascites in gynaecological cancer 2019 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 157 participants
  Very low

Abdominal paracentesis and intraperitoneal infusion of catumaxomab vs abdominal paracentesis alone

The review found no eligible studies for this question.

• Management of drainage for malignant ascites in gynaecological cancer 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Abdominal paracentesis and intraperitoneal infusion of catumaxomab vs abdominal paracentesis alone

The review found no eligible studies for this question.

• Management of drainage for malignant ascites in gynaecological cancer 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Abdominal paracentesis and intraperitoneal infusion of catumaxomab vs abdominal paracentesis alone

The review found no eligible studies for this question.

• Management of drainage for malignant ascites in gynaecological cancer 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Combination of lidocaine intraperitoneal instillation plus intramuscular morphine vs IM morphine

• Interventions for intra‐operative pain relief during postpartum mini‐laparotomy tubal ligation 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  Very low