Continuous showed no clear difference in necrotising enterocolitis (NEC) compared with intermittent bolus (nasogastric and orogastric tube) milk feeding ‐… (low certainty).

1 finding from 1 review

Continuous nasogastric milk feeding versus intermittent bolus milk feeding for preterm infants less than 1500 grams 2021 · Cochrane Headline outcomes only
RR 1.19 [0.67, 2.11]
4 studies · 372 participants
Low

Intervention not reported

Time taken to establish full gavage feeding (days) · intermittent bolus gavage tube feeding of preterm and low birth weight infants

1 finding from 1 review

Push versus gravity for intermittent bolus gavage tube feeding of preterm and low birth weight infants 2021 · Cochrane Headline outcomes only
no estimate extracted
0 participants
GRADE not reported

Intervention not reported

Feeding intolerance (number of episodes per day) · intermittent bolus gavage tube feeding of preterm and low birth weight infants

1 finding from 1 review

Push versus gravity for intermittent bolus gavage tube feeding of preterm and low birth weight infants 2021 · Cochrane Headline outcomes only
no estimate extracted
0 participants
GRADE not reported

Intervention not reported

Respiratory rate (breaths per minute) at completion of feed · intermittent bolus gavage tube feeding of preterm and low birth weight infants

1 finding from 1 review

Push versus gravity for intermittent bolus gavage tube feeding of preterm and low birth weight infants 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 31 participants
Very low

Intervention not reported

Respiratory rate (breaths per minute) · intermittent bolus gavage tube feeding of preterm and low birth weight infants

1 finding from 1 review

Push versus gravity for intermittent bolus gavage tube feeding of preterm and low birth weight infants 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 31 participants
Very low

Intervention not reported

Heart rate (beats per minute) at completion of feed · intermittent bolus gavage tube feeding of preterm and low birth weight infants

1 finding from 1 review

Push versus gravity for intermittent bolus gavage tube feeding of preterm and low birth weight infants 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 31 participants
Very low

Intervention not reported

Heart rate (beats per minute) · intermittent bolus gavage tube feeding of preterm and low birth weight infants

1 finding from 1 review

Push versus gravity for intermittent bolus gavage tube feeding of preterm and low birth weight infants 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 31 participants
Very low

HFNC vs nasal intermittent positive pressure ventilation

BPD (supplemental oxygen/respiratory support at 36 weeks' postmenstrual age if born < 32 weeks' gestation, or 28 days if born ≥ 32 weeks' gestation) · preterm infants requiring primary respiratory support

Nasal high flow showed no clear difference in BPD (supplemental oxygen/respiratory support at 36 weeks'… compared with nasal intermittent positive pressure ventilation (low certainty).

1 finding from 1 review

Nasal high flow therapy for primary respiratory support in preterm infants 2023 · Cochrane Headline outcomes only
RR 1.19 [0.66, 2.12]
3 studies · 271 participants
Low

HFNC vs nasal intermittent positive pressure ventilation

Treatment failure within 72 hours of trial entry · preterm infants requiring primary respiratory support

Nasal high flow showed no clear difference in treatment failure within 72 hours of trial entry compared with nasal intermittent positive pressure ventilation (moderate certainty).

1 finding from 1 review

Nasal high flow therapy for primary respiratory support in preterm infants 2023 · Cochrane Headline outcomes only
RR 1.27 [0.9, 1.79]
4 studies · 343 participants
Moderate

HFNC vs nasal intermittent positive pressure ventilation

Mechanical ventilation within 72 hours of trial entry · preterm infants requiring primary respiratory support

Nasal high flow showed no clear difference in mechanical ventilation within 72 hours of trial entry compared with nasal intermittent positive pressure ventilation (moderate certainty).

1 finding from 1 review

Nasal high flow therapy for primary respiratory support in preterm infants 2023 · Cochrane Headline outcomes only
RR 0.91 [0.62, 1.33]
4 studies · 343 participants
Moderate

HFNC vs nasal intermittent positive pressure ventilation

Pneumothorax · preterm infants requiring primary respiratory support

Nasal high flow showed no clear difference in pneumothorax (during assigned treatment) compared with nasal intermittent positive pressure ventilation (moderate certainty).

1 finding from 1 review

Nasal high flow therapy for primary respiratory support in preterm infants 2023 · Cochrane Headline outcomes only
RR 0.78 [0.4, 1.53]
4 studies · 344 participants
Moderate

HFNC vs nasal intermittent positive pressure ventilation

Nasal trauma (during assigned treatment) · preterm infants requiring primary respiratory support

Nasal high flow probably leads to lower nasal trauma (during assigned treatment) compared with nasal intermittent positive pressure ventilation (moderate certainty).

1 finding from 1 review

Nasal high flow therapy for primary respiratory support in preterm infants 2023 · Cochrane Headline outcomes only
RR 0.21 [0.09, 0.47]
3 studies · 272 participants
Moderate

HFNC vs nasal intermittent positive pressure ventilation

Death (before hospital discharge) or BPD (supplemental oxygen/respiratory support at 36 weeks' postmenstrual age if born < 32 weeks' gestation, or 28 days if born ≥ 32 weeks' gestation) · preterm infants requiring primary respiratory support

It is very uncertain whether nasal high flow changes death (before hospital discharge) or BPD (supplemental… compared with nasal intermittent positive pressure ventilation (very low certainty).

1 finding from 1 review

Nasal high flow therapy for primary respiratory support in preterm infants 2023 · Cochrane Headline outcomes only
RR 0.64 [0.3, 1.37]
2 studies · 182 participants
Very low

HFNC vs nasal intermittent positive pressure ventilation

Mortality before hospital discharge · preterm infants requiring primary respiratory support

Nasal high flow showed no clear difference in death (before hospital discharge) compared with nasal intermittent positive pressure ventilation (low certainty).

1 finding from 1 review

Nasal high flow therapy for primary respiratory support in preterm infants 2023 · Cochrane Headline outcomes only
RR 0.78 [0.36, 1.69]
3 studies · 254 participants
Low

Continuous glucose monitoring system vs intermittent modalities

Cerebral palsy ‐ not reported · infants at risk of hypoglycaemia or hyperglycaemia

The review found no eligible studies for this question.

1 finding from 1 review

Continuous glucose monitoring for the prevention of morbidity and mortality in preterm infants 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found