Findings

What do systematic reviews say?

116 questions · 117 findings · 11 reviews · ENT

Sort:Best matchNewest Highest certainty Download CSV

No studies found 44 · 37.6%GRADE not reported 0 · 0%Very low 28 · 23.9%Low 32 · 27.4%Moderate 11 · 9.4%High 2 · 1.7%

Topical quinolone vs quinolones

Suspected ototoxicity · people (of any age) with CSOM

1 finding from 1 review

Topical versus systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 265 participants
Very low

Topical quinolone vs intramuscular gentamicin

Health‐related quality of life · adults with CSOM

The review found no eligible studies for this question.

1 finding from 1 review

Topical versus systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topical quinolone vs intramuscular gentamicin

Ear pain (otalgia) or discomfort or local irritation · adults with CSOM

1 finding from 1 review

Topical versus systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 60 participants
Very low

Topical quinolone vs intramuscular gentamicin

Hearing · adults with CSOM

1 finding from 1 review

Topical versus systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 60 participants
Very low

Topical quinolone vs intramuscular gentamicin

Serious complications · adults with CSOM

1 finding from 1 review

Topical versus systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 60 participants
Very low

Topical quinolone vs intramuscular gentamicin

Suspected ototoxicity · adults with CSOM

1 finding from 1 review

Topical versus systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 60 participants
Very low

Topical quinolone vs oral amoxicillin‐clavulanic acid combination

Resolution of ear discharge ‐ measured at 1 to 2 weeks · adults with CSOM

It is very uncertain whether topical quinolone changes resolution of ear discharge ‐ 1 to 2 weeks compared with oral amoxicillin‐clavulanic acid combination (very low certainty).

1 finding from 1 review

Topical versus systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
RR 2.93 [1.5, 5.72]
1 study · 56 participants
Very low

Topical quinolone vs oral amoxicillin‐clavulanic acid combination

Resolution of ear discharge ‐ measured after 4 weeks · adults with CSOM

The review found no eligible studies for this question.

1 finding from 1 review

Topical versus systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topical quinolone vs oral amoxicillin‐clavulanic acid combination

Health‐related quality of life · adults with CSOM

The review found no eligible studies for this question.

1 finding from 1 review

Topical versus systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topical quinolone vs oral amoxicillin‐clavulanic acid combination

Ear pain (otalgia) or discomfort or local irritation · adults with CSOM

1 finding from 1 review

Topical versus systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 56 participants
Very low

Topical quinolone vs oral amoxicillin‐clavulanic acid combination

Hearing · adults with CSOM

1 finding from 1 review

Topical versus systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 56 participants
Very low

Topical quinolone vs oral amoxicillin‐clavulanic acid combination

Serious complications · adults with CSOM

The review found no eligible studies for this question.

1 finding from 1 review

Topical versus systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topical quinolone vs oral amoxicillin‐clavulanic acid combination

Suspected ototoxicity · adults with CSOM

1 finding from 1 review

Topical versus systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 56 participants
Very low

Topical quinolone vs intramuscular gentamicin

Resolution of ear discharge ‐ measured at 1 to 2 weeks · adults with CSOM

The review found no eligible studies for this question.

1 finding from 1 review

Topical versus systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topical quinolone vs intramuscular gentamicin

Resolution of ear discharge ‐ measured after 4 weeks · adults with CSOM

The review found no eligible studies for this question.

1 finding from 1 review

Topical versus systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topical quinolone vs boric acid

Quality of life ‐ not measured · chronic suppurative otitis media

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotics versus topical antiseptics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topical quinolone vs boric acid

Ear pain (otalgia) or discomfort or local irritation · chronic suppurative otitis media

Topical antibiotics (quinolones) may leads to lower ear pain, discomfort, irritation compared with boric acid (low certainty).

1 finding from 1 review

Antibiotics versus topical antiseptics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
RR 0.56 [0.32, 0.98]
2 studies · 510 participants
Low

Topical quinolone vs boric acid

Average change in hearing from baseline · chronic suppurative otitis media

1 finding from 1 review

Antibiotics versus topical antiseptics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 390 participants
Low

Topical quinolone vs boric acid

Serious complications ‐ not measured · chronic suppurative otitis media

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotics versus topical antiseptics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topical quinolone vs boric acid

Suspected ototoxicity ‐ not measured · chronic suppurative otitis media

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotics versus topical antiseptics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found