Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

94 questions · 96 findings · 11 reviews

No studies found 17 · 17.7%GRADE not reported 1 · 1%Very low 35 · 36.5%Low 24 · 25%Moderate 17 · 17.7%High 2 · 2.1%

Proton pump inhibitors (PPI) vs H2RA, placebo or no treatment

Proportion of participants with stigmata of recent haemorrhage at index endoscopy · people with upper gastrointestinal bleeding prior to endoscopic diagnosis

Proton pump inhibitor treatment showed no clear difference in proportion of participants with stigmata of recent haemorrhage at… compared with H2RA, placebo or no treatment (low certainty).

1 finding from 1 review

Proton pump inhibitors (PPI) vs H2RA, placebo or no treatment

Endoscopic haemostatic treatment at index endoscopy · people with upper gastrointestinal bleeding prior to endoscopic diagnosis

Proton pump inhibitor treatment probably leads to lower endoscopic haemostatic treatment at index endoscopy compared with H2RA, placebo or no treatment (moderate certainty).

1 finding from 1 review

Mitomycin C dacryocystorhinostomy vs dacryocystorhinostomy alone

Ostium size on nasal endoscopy · nasolacrimal duct obstruction

Mitomycin C dacryocystorhinostomy showed no clear difference in ostium size on nasal endoscopy compared with dacryocystorhinostomy alone (low certainty).

2 findings from 1 review

Epinephrine vs epinephrine and any second endoscopic method

Recurrent and persistent bleeding overall rates with or without second‐look endoscopy Rebleeding (persistent or recurrent bleeding) · patients with high‐risk bleeding ulcers

Epinephrine probably leads to lower recurrent and persistent bleeding overall rates with or without… compared with epinephrine and any second endoscopic method (moderate certainty).

1 finding from 1 review

Epinephrine vs epinephrine and any second endoscopic method

Adverse effects of endoscopy therapy Adverse effects · patients with high‐risk bleeding ulcers

Epinephrine probably leads to higher adverse effects of endoscopy therapy Adverse effects compared with epinephrine and any second endoscopic method (moderate certainty).

1 finding from 1 review

Intervention not reported

The ability of OWSC, when seen to reach the colon on · Adults 18 yrs and over with malignant bowel obstruction (MBO) as defined by the International Conference on MBO, with no indication for…

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

The rate of resolution of MBO with medical management only in patients receiving OWSC compared with those not receiving it (therapeutic). · Adults 18 yrs and over with malignant bowel obstruction (MBO) as defined by the International Conference on MBO, with no indication for…

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Gastrointestinal adverse effects (increased abdominal pain, nausea, vomiting). · Adults 18 yrs and over with malignant bowel obstruction (MBO) as defined by the International Conference on MBO, with no indication for…
1 finding from 1 review

Intervention not reported

Extra‐abdominal complications (aspiration pneumonia, hypersensitivity reactions). · Adults 18 yrs and over with malignant bowel obstruction (MBO) as defined by the International Conference on MBO, with no indication for…
1 finding from 1 review

Intervention not reported

Length of hospital stay. · Adults 18 yrs and over with malignant bowel obstruction (MBO) as defined by the International Conference on MBO, with no indication for…

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Time from administration of OWSC to resolution of MBO. · Adults 18 yrs and over with malignant bowel obstruction (MBO) as defined by the International Conference on MBO, with no indication for…

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Survival time from onset of inoperable MBO until death. · Adults 18 yrs and over with malignant bowel obstruction (MBO) as defined by the International Conference on MBO, with no indication for…

The review found no eligible studies for this question.

1 finding from 1 review

Intravenous midazolam vs placebo

Anterograde amnesia (defined by number of participants who recalled the procedure) · adults requiring sedation before gastrointestinal endoscopy and bronchoscopy

The review found no eligible studies for this question.

1 finding from 1 review