Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

67 questions · 68 findings · 11 reviews

No studies found 19 · 27.9%GRADE not reported 0 · 0%Very low 14 · 20.6%Low 16 · 23.5%Moderate 19 · 27.9%High 0 · 0%

Subfascial endoscopic perforator vein surgery (SEPS) + compression vs compression alone

Recurrence of ulcers · people with venous leg ulcers

It is very uncertain whether subfascial endoscopic perforator vein surgery (SEPS) + compression changes ulcer recurrence at 24 months compared with compression alone (very low certainty).

1 finding from 1 review

Sinonasal debridement vs no debridement

Postoperative endoscopic appearance of the sinonasal surgical cavities: Lund‐Kennedy endoscopic score (range 1 to 10) · adult patients who underwent primary endoscopic sinus surgery, with a diagnosis of recurrent acute or chronic rhinosinusitis

Sinonasal debridement showed no clear difference in postoperative endoscopic appearance of the sinonasal surgical… compared with no debridement (low certainty).

1 finding from 1 review

Open surgery vs ERCP

Retained stones after primary intervention · with common bile duct stones

Open surgery probably leads to lower retained stones after primary intervention compared with ERCP (moderate certainty).

1 finding from 1 review

Proton pump inhibitors (PPI) vs H2RA, placebo or no treatment

Surgery ‐ within 30 days · people with upper gastrointestinal bleeding prior to endoscopic diagnosis

Proton pump inhibitor treatment showed no clear difference in surgery ‐ within 30 days compared with H2RA, placebo or no treatment (low certainty).

1 finding from 1 review