Femoral neck bone mineral density (FN-BMD) · European-ancestry adults
Genetically predicted dental caries (DMFS) had no causal effect on femoral neck BMD.
1 finding from 1 review
Femur fracture · European-ancestry adults
Genetically predicted dental caries (DMFS) had no significant causal effect on fracture of femur (multivariable MR, OR 1.069).
2 findings from 1 review
Dental caries · Children and adolescents aged 0-18 years with non-syndromic cleft lip and palate (CLP)
Pooling 3 studies, children/adolescents with CLP were about 2.03 times more likely to have dental caries than non-CLP controls (p<0.005; low heterogeneity), though most included studies were at high risk of bias; the evidence is ungraded.
1 finding from 1 review
Development of post-radiotherapy dental complications (caries, fractured teeth, periapical infection, periodontal disease, osteoradionecrosis) · Patients diagnosed with head and neck cancer planned to undergo any type of radiotherapy (external beam, intensity modulated,…
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
0 studies
No studies found
Development of post-radiotherapy dental complications (caries, fractured teeth, periapical infection, periodontal disease, osteoradionecrosis) · Patients diagnosed with head and neck cancer planned to undergo any type of radiotherapy (external beam, intensity modulated,…
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
0 studies
No studies found
Systemic antibiotic prophylaxis (any regimen; topical therapy excluded) administered before and/or after tooth extraction vs Placebo
Outcome not reported · Patients undergoing tooth extraction for severe dental caries or periodontal disease in general dental practice (non-third-molar / decayed…
The review found no eligible studies for this question.
1 finding from 1 review
Lumbar spine and pelvis fracture · European GWAS participants
The SVMR Weighted Median interval included the null.
3 findings from 1 review
OR 1.058 [0.966, 1.158]
490700 participants
GRADE not reported
OR 1.036 [0.956, 1.122]
490700 participants
GRADE not reported
OR 1.055 [0.983, 1.132]
490700 participants
GRADE not reported
Osteoporosis · European GWAS participants
The SVMR MR-Egger interval included the null.
4 findings from 1 review
OR 1.001 [0.918, 1.093]
483725 participants
GRADE not reported
OR 0.998 [0.934, 1.067]
483725 participants
GRADE not reported
OR 1.002 [0.925, 1.086]
483725 participants
GRADE not reported
Show 1 more finding
OR 0.998 [0.933, 1.067]
483725 participants
GRADE not reported
Osteoporosis with pathological fracture · European GWAS participants
The SVMR Weighted Median interval included the null.
3 findings from 1 review
OR 0.985 [0.846, 1.146]
376746 participants
GRADE not reported
OR 1.003 [0.874, 1.151]
376746 participants
GRADE not reported
OR 0.953 [0.813, 1.117]
376746 participants
GRADE not reported
Forearm fracture · European GWAS participants
The SVMR Weighted Median interval included the null.
3 findings from 1 review
OR 0.992 [0.945, 1.042]
490889 participants
GRADE not reported
OR 0.994 [0.948, 1.042]
490889 participants
GRADE not reported
OR 0.990 [0.950, 1.032]
490889 participants
GRADE not reported
Lumbar spine and pelvis fracture · European GWAS participants
The MVMR MR-Egger interval included the null.
1 finding from 1 review
OR 1.062 [0.991, 1.137]
490700 participants
GRADE not reported
Osteoporosis with pathological fracture · European-ancestry adults
Genetically predicted periodontitis had no causal effect on osteoporosis with pathological fracture (single-variable MR, OR 1.003).
2 findings from 1 review
Lumbar spine bone mineral density (BMD) · European GWAS participants
The MVMR IVW interval included zero.
1 finding from 1 review
Lumbar spine and pelvis fracture · European-ancestry adults
Genetically predicted periodontitis had no causal effect on fracture of lumbar spine and pelvis (multivariable MR, OR 1.060).
2 findings from 1 review
Forearm fracture · European GWAS participants
The MVMR MR-Egger interval included the null.
1 finding from 1 review
OR 0.992 [0.950, 1.036]
490889 participants
GRADE not reported
Femoral neck bone mineral density (FN-BMD) · European-ancestry adults
Genetically predicted periodontitis had no causal effect on femoral neck BMD.
1 finding from 1 review
Femur fracture · European-ancestry adults
Genetically predicted periodontitis had no causal effect on fracture of femur (multivariable MR, OR 1.034).
2 findings from 1 review
Intervention not reported
Postmenopausal osteoporosis with pathological fracture
The intervention led to higher postmenopausal osteoporosis with pathological fracture; GRADE not reported.
1 finding from 1 review
OR 1.401 [1.040, 1.887]
Studies not reported
GRADE not reported
Osteoporosis · European-ancestry adults
Genetically predicted periodontitis had no causal effect on osteoporosis (multivariable MR, OR 1.000).
2 findings from 1 review
Femur fracture · European GWAS participants
The MVMR MR-Egger interval included the null.
1 finding from 1 review
OR 1.024 [0.960, 1.093]
489106 participants
GRADE not reported