Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

45 questions · 45 findings · 19 reviews · Developmental, Psychosocial and Learning Problems

No studies found 7 · 15.6%GRADE not reported 0 · 0%Very low 23 · 51.1%Low 12 · 26.7%Moderate 3 · 6.7%High 0 · 0%

Intervention not reported

Withdrawal of methylphenidate due to adverse events of unknown severity Measured by: proportion of participants withdrawn from treatment Average study duration (range): 4.6 months (21 days to 36 months) · children and adolescents aged 18 years and under diagnosed with ADHD
1 finding from 1 review

Intervention not reported

Withdrawal of methylphenidate for unknown reasons Measure by: proportion of participants withdrawn from treatment Average study duration (range): 6.13 months (1 day to 36 months) · children and adolescents aged 18 years and under diagnosed with ADHD
1 finding from 1 review

Parent‐mediated communication intervention vs no intervention

Children's ability to communicate effectively in everyday life: taking turns in conversation, initiating conversation and responding to others' conversational gambits · children up to 5 years of age with a communication difficulty associated with any non‐progressive motor disorder acquired before 2 years…
1 finding from 1 review

Home (point‐of‐use) fortification of foods with multiple micronutrient powders vs placebo or no intervention

Diarrhoea · preschool and school‐age children

Point‐of‐use fortification of foods with micronutrients powders (MNP) showed no clear difference in diarrhoea (≥ 3 liquid stools per day) compared with no intervention or placebo (low certainty).

1 finding from 1 review

Simethicone vs placebo

Reduction in crying duration Difference between final values (hours per day of crying) · infants with colic defined by recognised criteria

It is very uncertain whether simethicone changes reduction in crying duration Difference between final values (hours… compared with placebo (very low certainty).

1 finding from 1 review

Herbal agents vs placebo

Reduction in crying duration Difference before and after treatment (hours per day of crying) · patients with infantile colic

Herbal agents may leads to higher reduction in crying duration Difference before and after treatment… compared with placebo (low certainty).

1 finding from 1 review

Sugar vs placebo

Reduction in crying duration Difference before and after treatment (hours per day of crying) · infants with colic defined by recognised criteria

It is very uncertain whether sugar changes reduction in crying duration Difference before and after treatment… compared with placebo (very low certainty).

1 finding from 1 review