Findings

What do systematic reviews say?

23 questions · 23 findings · 5 reviews

No studies found 1 · 4.3%GRADE not reported 0 · 0%Very low 14 · 60.9%Low 6 · 26.1%Moderate 2 · 8.7%High 0 · 0%

Postoperative amenorrhoea at 12 months or less · women with heavy menstrual bleeding

It is very uncertain whether gnRH analogues changes postoperative amenorrhoea at 12 months or less compared with danazol (very low certainty).

1 finding from 1 review

Relief of painful symptoms ‐ Dysmenorrhoea · patients with pain associated with endometriosis

It is very uncertain whether gnRHas changes relief of painful symptoms ‐ Dysmenorrhoea compared with danazol (very low certainty).

1 finding from 1 review

Gonadotrophin‐releasing hormone analogues for pain associated with endometriosis 2010 · Cochrane Headline outcomes only
RR 0.98 [0.92, 1.04]
7 studies · 666 participants
Very low

Overall resolution ‐ Overall resolution/improvement · patients with pain associated with endometriosis

GnRHas may leads to higher overall resolution ‐ Overall resolution/improvement compared with danazol (low certainty).

1 finding from 1 review

Gonadotrophin‐releasing hormone analogues for pain associated with endometriosis 2010 · Cochrane Headline outcomes only
RR 1.1 [1.01, 1.21]
9 studies · 1046 participants
Low