Postoperative amenorrhoea at 12 months or less · women with heavy menstrual bleeding
Danazol showed no clear difference in postoperative amenorrhoea at 12 months or less compared with no pretreatment (low certainty).
1 finding from 1 review
RR 1.05 [0.8, 1.39]
179 participants
Low
Postoperative amenorrhoea at 12 months or less · women with heavy menstrual bleeding
Danazol may leads to higher postoperative amenorrhoea at 12 months or less compared with progestogens (low certainty).
1 finding from 1 review
RR 1.89 [1.12, 3.18]
103 participants
Low
Postoperative amenorrhoea at 12 months or less · women with heavy menstrual bleeding
GnRHa or danazol showed no clear difference in postoperative amenorrhoea at 12 months or less compared with no pretreatment (low certainty).
1 finding from 1 review
RR 1.13 [0.89, 1.43]
280 participants
Low
Relief of pain · patients with pain associated with endometriosis
1 finding from 1 review
Relief of overall pain ‐ reported as pelvic pain ‐ 3 months · patients with pain associated with endometriosis
1 finding from 1 review
Relief of overall pain ‐ reported as dysmenorrhoea ‐ 6 months · patients with pain associated with endometriosis
1 finding from 1 review
Relief of overall pain ‐ reported as pelvic induration ‐ 6 months · patients with pain associated with endometriosis
1 finding from 1 review
Relief of overall pain ‐ reported as pelvic tenderness ‐ 6 months · patients with pain associated with endometriosis
1 finding from 1 review
Relief of overall pain ‐ reported as pelvic tenderness, partly resolved ‐ 6 months · patients with pain associated with endometriosis
It is very uncertain whether gnRHas changes relief of overall pain ‐ reported as pelvic tenderness, partly… compared with danazol (very low certainty).
1 finding from 1 review
Relief of overall pain ‐ reported as pelvic tenderness, complete resolved ‐ 6 months · patients with pain associated with endometriosis
It is very uncertain whether gnRHas changes relief of overall pain ‐ reported as pelvic tenderness, complete… compared with danazol (very low certainty).
1 finding from 1 review
MBL (mL per cycle) · women with heavy menstrual bleeding
1 finding from 1 review
Number of days' bleeding · women with heavy menstrual bleeding
1 finding from 1 review
Quality of life · women with heavy menstrual bleeding
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Side effects ‐ hot flushes · women with symptomatic endometriosis
It is very uncertain whether gestrinone changes side effects: hot flushes compared with danazol (very low certainty).
1 finding from 1 review
Adverse effects: acne · women with symptomatic endometriosis
Gestrinone showed no clear difference in side effects: acne compared with danazol (low certainty).
1 finding from 1 review
Pelvic pain · women with symptomatic endometriosis
It is very uncertain whether gestrinone changes pelvic pain: none or mild compared with danazol (very low certainty).
1 finding from 1 review
Dysmenorrhoea: none or mild · women with symptomatic endometriosis
It is very uncertain whether gestrinone changes dysmenorrhoea: none or mild compared with danazol (very low certainty).
1 finding from 1 review
Dyspareunia: none or mild · women with symptomatic endometriosis
It is very uncertain whether gestrinone changes dyspareunia: none or mild compared with danazol (very low certainty).
1 finding from 1 review
Side effects ‐ hirsutism · women with symptomatic endometriosis
It is very uncertain whether gestrinone changes side effects: hirsutism compared with danazol (very low certainty).
1 finding from 1 review
Decreased breast size · women with symptomatic endometriosis
Gestrinone may leads to lower decreased breast size compared with danazol (low certainty).
1 finding from 1 review