Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

139 questions · 139 findings · 11 reviews · Schizophrenia

No studies found 22 · 15.8%GRADE not reported 31 · 22.3%Very low 56 · 40.3%Low 24 · 17.3%Moderate 6 · 4.3%High 0 · 0%

Summary of findings table ‐ Cognitive behavioural therapy plus standard care vs control

Risk for at least one adverse event per patient · recent‐onset psychosis (less than three years since the start of psychotic symptoms and either first or second psychotic episode)

It is very uncertain whether summary of findings table ‐ Cognitive behavioural therapy plus… changes adverse events ‐ participants with at least one adverse event ‐ < 12… compared with control (very low certainty).

1 finding from 1 review

Group C cognitive behavioural therapy: cognitive behavioural therapy + placebo vs placebo or supportive treatment

Prodromal symptoms: transition to psychosis Endpoint data (events) · people in the prodromal stage of psychosis

It is very uncertain whether group C cognitive behavioural therapy: cognitive behavioural therapy… changes prodromal symptoms: transition to psychosis Endpoint data (events) compared with supportive therapy + placebo (very low certainty).

1 finding from 1 review