Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

40 questions · 40 findings · 5 reviews

No studies found 5 · 12.5%GRADE not reported 0 · 0%Very low 18 · 45%Low 12 · 30%Moderate 5 · 12.5%High 0 · 0%

Intervention not reported

Beta‐blockers + variceal band ligation(1 RCT, 173 participants) · people with liver cirrhosis and oesophageal varices with no history of bleeding

The intervention may leads to lower beta‐blockers + variceal band ligation(1 RCT, 173 participants) (low certainty).

1 finding from 1 review

Intervention not reported

Variceal band ligation(17 RCTs, 1640 participants) · people with liver cirrhosis and oesophageal varices with no history of bleeding

It is very uncertain whether the intervention changes variceal band ligation(17 RCTs, 1640 participants) (very low certainty).

1 finding from 1 review

Intervention not reported

Beta‐blockers + variceal band ligation(2 RCTs, 313 participants) · people with liver cirrhosis and oesophageal varices with no history of bleeding

It is very uncertain whether the intervention changes beta‐blockers + variceal band ligation(2 RCTs, 313 participants) (very low certainty).

1 finding from 1 review

Intervention not reported

Beta‐blockers plus Nitrates plus Variceal band ligation(No direct RCT) · people with liver cirrhosis and previous oesophageal variceal bleeding

The intervention showed no clear difference in beta‐blockers plus Nitrates plus Variceal band ligation(No direct RCT) (low certainty).

1 finding from 1 review

Intervention not reported

Beta‐blockers plus Variceal band ligation(No direct RCT) · people with liver cirrhosis and previous oesophageal variceal bleeding

The intervention showed no clear difference in beta‐blockers plus Variceal band ligation(No direct RCT) (low certainty).

1 finding from 1 review

Cyanoacrylate vs band ligation

Mortality Total of deaths and the end of · acute bleeding gastric varices in people with portal hypertension

It is very uncertain whether cyanoacrylate changes mortality Total of deaths and the end of compared with band ligation (very low certainty).

1 finding from 1 review

Cyanoacrylate vs band ligation

Failure of intervention Continuous variceal bleeding after intervention · acute bleeding gastric varices in people with portal hypertension

It is very uncertain whether cyanoacrylate changes failure of intervention Continuous variceal bleeding after… compared with band ligation (very low certainty).

1 finding from 1 review

Cyanoacrylate vs band ligation

Re‐bleeding Re‐bleeding after the bleeding was controlled in the first intervention · acute bleeding gastric varices in people with portal hypertension

Cyanoacrylate may leads to lower re‐bleeding Re‐bleeding after the bleeding was controlled in the… compared with band ligation (low certainty).

1 finding from 1 review

Cyanoacrylate vs band ligation

Complications (general) Number of total complications · acute bleeding gastric varices in people with portal hypertension

It is very uncertain whether cyanoacrylate changes complications (general) Number of total complications compared with band ligation (very low certainty).

1 finding from 1 review

Cyanoacrylate vs band ligation

Control of bleeding Success in control the active variceal bleeding · acute bleeding gastric varices in people with portal hypertension

It is very uncertain whether cyanoacrylate changes control of bleeding Success in control variceal bleeding compared with band ligation (very low certainty).

1 finding from 1 review