All‐cause mortality · children with portal hypertension and large oesophageal varices, without previous gastrointestinal bleeding or beta‐blocker treatment
It is very uncertain whether band ligation changes all‐cause mortality compared with sham or no intervention (very low certainty).
1 finding from 1 review
Serious adverse events Idiopathic thrombocytopaenic purpura · children with portal hypertension and large oesophageal varices, without previous gastrointestinal bleeding or beta‐blocker treatment
It is very uncertain whether band ligation changes serious adverse events Idiopathic thrombocytopaenic purpura compared with sham or no intervention (very low certainty).
1 finding from 1 review
Health‐related quality of life · children with portal hypertension and large oesophageal varices, without previous gastrointestinal bleeding or beta‐blocker treatment
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Oesophageal variceal bleeding · children with portal hypertension and large oesophageal varices, without previous gastrointestinal bleeding or beta‐blocker treatment
It is very uncertain whether band ligation changes oesophageal variceal bleeding compared with sham or no intervention (very low certainty).
1 finding from 1 review
Adverse events considered non‐serious · children with portal hypertension and large oesophageal varices, without previous gastrointestinal bleeding or beta‐blocker treatment
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Outcomes* · adults with oesophageal varices
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
All‐cause mortality · adults with oesophageal varices
Band ligation probably leads to lower mortality compared with no intervention (moderate certainty).
1 finding from 1 review
Upper gastrointestinal bleeding · adults with oesophageal varices
Band ligation probably leads to lower upper gastrointestinal bleeding compared with no intervention (moderate certainty).
1 finding from 1 review
Serious adverse events · adults with oesophageal varices
Band ligation probably leads to lower serious adverse events compared with no intervention (moderate certainty).
1 finding from 1 review
Variceal bleeding · adults with oesophageal varices
Band ligation probably leads to lower variceal bleeding compared with no intervention (moderate certainty).
1 finding from 1 review
Non‐serious adverse events · adults with oesophageal varices
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Health‐related quality of life · adults with oesophageal varices
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
Variceal band ligation(5 RCTs, 372 participants) · people with liver cirrhosis and oesophageal varices with no history of bleeding
It is very uncertain whether the intervention changes variceal band ligation(5 RCTs, 372 participants) (very low certainty).
1 finding from 1 review
OR 0.75 [0.02, 23.24]
Studies not reported
Very low
Intervention not reported
Variceal band ligation(1 RCT, 168 participants) · people with liver cirrhosis and oesophageal varices with no history of bleeding
1 finding from 1 review
no estimate extracted
Studies not reported
Low
Intervention not reported
Variceal band ligation(7 RCTs, 728 participants) · people with liver cirrhosis and oesophageal varices with no history of bleeding
It is very uncertain whether the intervention changes variceal band ligation(7 RCTs, 728 participants) (very low certainty).
1 finding from 1 review
OR 1.6 [0.54, 5.15]
Studies not reported
Very low
Intervention not reported
Variceal band ligation(4 RCTs, 480 participants) · people with liver cirrhosis and oesophageal varices with no history of bleeding
1 finding from 1 review
no estimate extracted
Studies not reported
Low
Intervention not reported
Beta‐blockers + variceal band ligation(1 RCT, 140 participants) · people with liver cirrhosis and oesophageal varices with no history of bleeding
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Intervention not reported
Variceal band ligation(5 RCTs, 380 participants) · people with liver cirrhosis and oesophageal varices with no history of bleeding
It is very uncertain whether the intervention changes variceal band ligation(5 RCTs, 380 participants) (very low certainty).
1 finding from 1 review
HR 1.41 [0.83, 2.43]
Studies not reported
Very low
Intervention not reported
Variceal band ligation(3 RCTs, 330 participants) · people with liver cirrhosis and oesophageal varices with no history of bleeding
It is very uncertain whether the intervention changes variceal band ligation(3 RCTs, 330 participants) (very low certainty).
1 finding from 1 review
HR 0.8 [0.47, 1.36]
Studies not reported
Very low
Intervention not reported
Variceal band ligation(9 RCTs, 879 participants) · people with liver cirrhosis and oesophageal varices with no history of bleeding
It is very uncertain whether the intervention changes variceal band ligation(9 RCTs, 879 participants) (very low certainty).
1 finding from 1 review
HR 0.72 [0.33, 1.51]
Studies not reported
Very low