Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

37 questions · 38 findings · 13 reviews · Schizophrenia

No studies found 1 · 2.6%GRADE not reported 3 · 7.9%Very low 17 · 44.7%Low 11 · 28.9%Moderate 6 · 15.8%High 0 · 0%

Life skills programme vs usual care

Life skills: No important change in household activity skills Royal Edinburgh Occupational Therapy Assessment Form · patients with chronic mental illnesses

It is very uncertain whether life skills programme changes life skills: No important change in household activity skills Royal… compared with standard care (very low certainty).

1 finding from 1 review

Life skills programme vs usual care

Life skills: No important change laundry skills Royal Edinburgh Occupational Therapy Assessment Form · patients with chronic mental illnesses

It is very uncertain whether life skills programme changes life skills: No important change laundry skills Royal Edinburgh… compared with standard care (very low certainty).

1 finding from 1 review

Life skills programme vs usual care

Life skills: No important change self‐care skills Royal Edinburgh Occupational Therapy Assessment Form · patients with chronic mental illnesses

It is very uncertain whether life skills programme changes life skills: No important change self‐care skills Royal Edinburgh… compared with standard care (very low certainty).

1 finding from 1 review

Sildenafil vs placebo

Sexual function: Objective assessment (Global efficacy questionnaire, improved erections) · patients with sexual dysfunction due to antipsychotic drug therapy

ADJUNCTIVE TREATMENT ‐ SPECIFIC: SILDENAFIL may leads to higher sexual function: Objective assessment (Global efficacy… compared with PLACEBO (low certainty).

1 finding from 1 review

ZOTEPINE vs CLOZAPINE

Global state: No clinically important response (as defined by the original studies) · patients with schizophrenia

It is very uncertain whether ZOTEPINE changes global state: No clinically important response (as defined by the… compared with CLOZAPINE (very low certainty).

1 finding from 1 review