Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

32 questions · 33 findings · 4 reviews · Skin

No studies found 11 · 33.3%GRADE not reported 0 · 0%Very low 7 · 21.2%Low 8 · 24.2%Moderate 7 · 21.2%High 0 · 0%

Topical antibiotics with steroids vs topical steroid

Global outcome (good or excellent improvement in symptoms or signs, or both) · people with eczema

Topical steroid plus topical antibiotic showed no clear difference in global outcome (good or excellent improvement in symptoms or signs,… compared with topical steroid (low certainty).

1 finding from 1 review

Topical antibiotics with steroids vs topical steroid

Minor adverse events not leading to withdrawal of treatment · people with eczema

It is very uncertain whether topical steroid plus topical antibiotic changes minor adverse events not requiring withdrawal from treatment compared with topical steroid (very low certainty).

1 finding from 1 review

Herbal medicines vs antibiotics alone

Remission · participants with acne

Herbal medicine showed no clear difference in secondary outcome: number of participants with remission (ITT‐best… compared with antibiotics (low certainty).

2 findings from 1 review