Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

98 questions · 101 findings · 24 reviews · Headline outcomes only

No studies found 16 · 15.8%GRADE not reported 8 · 7.9%Very low 42 · 41.6%Low 20 · 19.8%Moderate 14 · 13.9%High 1 · 1%

Anterior prolapse repair: native tissue vs polypropylene mesh

Repeat surgery for stress urinary incontinence (2 years) · women with anterior compartment pelvic organ prolapse

Anterior prolapse repair: native tissue showed no clear difference in repeat surgery for stress urinary incontinence (1‐2 years) compared with polypropylene mesh (low certainty).

1 finding from 1 review

Vaginal POP surgery with armed mesh vs anterior native tissue repair

One type of POP surgery vs another: armed anterior mesh vs anterior native tissue repair · continent women with POP

Vaginal POP surgery with armed mesh may leads to higher one type of POP surgery vs another: armed anterior mesh vs anterior… compared with anterior native tissue repair (low certainty).

1 finding from 1 review

Vaginal uterosacral colpopexy vs alternative vaginal native tissue apical suspension

Prolapse on examination ‐ Anterior compartment prolapse · women with apical vaginal prolapse

Vaginal uterosacral colpopexy showed no clear difference in prolapse on examination ‐ Anterior compartment prolapse compared with alternative vaginal native tissue apical suspension (moderate certainty).

1 finding from 1 review

PACK‐CXL with standard therapy vs Standard therapy alone (radiotherapy or chemoradiotherapy)

Proportion of participants with reduction in intraocular inflammation at 4 to 8 weeks Assessed by corneal keratic precipitates, anterior chamber cellular reaction, or other appropriate measure · participants of any age with confirmed cases of bacterial keratitis
1 finding from 1 review

Intervention not reported

Adverse events ‐ shallow anterior chamber · People undergoing trabeculectomy surgery with glaucoma

It is very uncertain whether the intervention changes adverse events ‐ shallow anterior chamber (very low certainty).

1 finding from 1 review

Regular‐dose postoperative 5‐Fluorouracil vs control

Complications ‐ shallow anterior chamber ‐ high risk of failure · participants with glaucoma surgery

Regular‐dose postoperative 5‐Fluorouracil showed no clear difference in complications ‐ shallow anterior chamber ‐ high risk of failure compared with control (moderate certainty).

1 finding from 1 review