Cochrane · systematic review · CD013108

Surgery for women with pelvic organ prolapse with or without stress urinary incontinence

Baessler, K, Christmann‐Schmid, C, Maher, C, et al. · Cochrane Database of Systematic Reviews · 2018 · Cochrane Library

Gynaecology and FertilityAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
8
current version
GRADE rated
8
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 2 · 25%Moderate 6 · 75%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

POP surgery with concomitant continence procedure compared to no concomitant continence procedure in women with POP and SUI

Population: women with POP and SUI
4 questions
OutcomeEffectEvidenceStatus / GRADE
Vaginal POP surgery with vs without MUS
POP surgery with concomitant continence procedure vs no concomitant continence procedure
RR 0.3 [0.19, 0.48]2 studies · 319 participantsModerate
Downgraded: risk of bias
Vaginal POP surgery with vs without MUS
POP surgery with concomitant continence procedure vs no concomitant continence procedure
RR 0.04 [0, 0.74]1 study · 134 participantsModerate
Downgraded: risk of bias
Vaginal POP surgery with concomitant vs delayed continence surgery: additional concomitant MUS vs delayed MUS
POP surgery with concomitant continence procedure vs no concomitant continence procedure
RR 0.41 [0.12, 1.37]1 study · 140 participantsModerate
Downgraded: risk of bias
Abdominal POP surgery with vs without concomitant continence surgery: additional Burch colposuspension vs sacrocolpopexy alone: 1‐year FU
POP surgery with concomitant continence procedure vs no concomitant continence procedure
RR 1.38 [0.74, 2.6]1 study · 47 participantsModerate
Downgraded: risk of bias

Vaginal POP surgery with concomitant continence procedure compared to no concomitant continence procedure in women with POP and occult SUI

Population: women with POP and occult SUI
1 question
OutcomeEffectEvidenceStatus / GRADE
Vaginal POP surgery with or without concomitant continence surgery: additional MUS vs vaginal repair alone
Vaginal POP surgery with concomitant continence procedure vs no concomitant continence procedure
RR 0.38 [0.26, 0.55]5 studies · 369 participantsModerate
Downgraded: risk of bias

Vaginal or abdominal POP surgery with concomitant continence procedure compared to no concomitant continence procedure in continent women with POP

Population: continent women with POP
2 questions
OutcomeEffectEvidenceStatus / GRADE
Vaginal POP surgery with or without concomitant continence surgery: additional MUS vs vaginal repair alone
Vaginal or abdominal POP surgery with concomitant continence procedure vs no concomitant continence procedure
RR 0.69 [0.47, 1]1 study · 220 participantsModerate
Downgraded: indirectness
Abdominal POP surgery with or without concomitant continence surgery: additional Burch colposuspension vs sacrocolpopexy alone
Vaginal or abdominal POP surgery with concomitant continence procedure vs no concomitant continence procedure
RR 1.31 [0.19, 9.01]2 studies · 379 participantsLow
Downgraded: imprecision, inconsistency, indirectness

Vaginal POP surgery with armed mesh compared to anterior native tissue repair for continent women with POP

Population: continent women with POP
1 question
OutcomeEffectEvidenceStatus / GRADE
One type of POP surgery vs another: armed anterior mesh vs anterior native tissue repair
Vaginal POP surgery with armed mesh vs anterior native tissue repair
RR 1.58 [1.05, 2.37]7 studies · 905 participantsLow
Downgraded: risk of bias