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Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

1,645 questions in 107 reviews · Wounds

current versions
No studies 651 · 39.6%Ungraded 84 · 5.1%Very low 554 · 33.7%Low 283 · 17.2%Moderate 64 · 3.9%High 9 · 0.5%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Subcuticular sutures vs surgical tapes
Cost · skin closure in non‐obstetric surgery
Subcuticular sutures for skin closure in non‐obstetric surgery (2020) · Cochrane
no estimate extracted3 studies · 315 participantsVery low
Subcuticular sutures vs surgical zippers
Surgical site infection Incidence of wound infection · skin closure in non‐obstetric surgery
Subcuticular sutures for skin closure in non‐obstetric surgery (2020) · Cochrane
RR 0.8 [0.08, 8.48]3 studies · 424 participantsVery low
Subcuticular sutures vs transdermal sutures
Wound dehiscence Incidence of wound dehiscence · skin closure in non‐obstetric surgery
Subcuticular sutures for skin closure in non‐obstetric surgery (2020) · Cochrane
RR 0.35 [0.08, 1.54]6 studies · 866 participantsVery low
Subcuticular sutures vs surgical zippers
Wound complications Incidence of wound complications · skin closure in non‐obstetric surgery
Subcuticular sutures for skin closure in non‐obstetric surgery (2020) · Cochrane
RR 0.55 [0.15, 2.04]3 studies · 424 participantsVery low
Subcuticular sutures vs surgical zippers
Wound dehiscence Incidence of wound dehiscence · skin closure in non‐obstetric surgery
Subcuticular sutures for skin closure in non‐obstetric surgery (2020) · Cochrane
RR 0.78 [0.19, 3.16]3 studies · 424 participantsVery low
Subcuticular sutures vs surgical zippers
Cosmesis of scar · skin closure in non‐obstetric surgery
Subcuticular sutures for skin closure in non‐obstetric surgery (2020) · Cochrane
no estimate extracted1 study · 90 participantsLow
Subcuticular sutures vs surgical zippers
Patient satisfaction · skin closure in non‐obstetric surgery
Subcuticular sutures for skin closure in non‐obstetric surgery (2020) · Cochrane
no estimate extractedNRNo studies
Subcuticular sutures vs surgical zippers
Wound closure time (minutes) · skin closure in non‐obstetric surgery
Subcuticular sutures for skin closure in non‐obstetric surgery (2020) · Cochrane
no estimate extracted3 studies · 424 participantsVery low
Subcuticular sutures vs surgical zippers
Cost · skin closure in non‐obstetric surgery
Subcuticular sutures for skin closure in non‐obstetric surgery (2020) · Cochrane
no estimate extracted1 study · 120 participantsLow
Subcuticular sutures vs transdermal sutures
Cosmesis of scar (cosmesis) · skin closure in non‐obstetric surgery
Subcuticular sutures for skin closure in non‐obstetric surgery (2020) · Cochrane
no estimate extracted5 studies · 950 participantsVery low
Subcuticular sutures vs transdermal sutures
Patient satisfaction (at 30 days) · skin closure in non‐obstetric surgery
Subcuticular sutures for skin closure in non‐obstetric surgery (2020) · Cochrane
MD 1.6 [1.32, 1.88]1 study · 290 participantsModerate
Subcuticular sutures vs transdermal sutures
Wound closure time (minutes) · skin closure in non‐obstetric surgery
Subcuticular sutures for skin closure in non‐obstetric surgery (2020) · Cochrane
MD 5.81 [5.13, 6.49]2 studies · 585 participantsModerate
Subcuticular sutures vs transdermal sutures
Cost · skin closure in non‐obstetric surgery
Subcuticular sutures for skin closure in non‐obstetric surgery (2020) · Cochrane
no estimate extracted1 study · 100 participantsLow
Subcuticular sutures vs skin staples
Surgical site infection Incidence of wound infection · skin closure in non‐obstetric surgery
Subcuticular sutures for skin closure in non‐obstetric surgery (2020) · Cochrane
RR 0.81 [0.64, 1.01]14 studies · 4163 participantsModerate
Subcuticular sutures vs skin staples
Wound complications Incidence of wound complications · skin closure in non‐obstetric surgery
Subcuticular sutures for skin closure in non‐obstetric surgery (2020) · Cochrane
RR 0.79 [0.64, 0.98]9 studies · 2973 participantsModerate
Electrical stimulation (plus standard care) vs sham/no ES (plus standard care)
Proportion of pressure ulcers healed (3 to 12 weeks) · people with pressure ulcers
Electrical stimulation for treating pressure ulcers (2020) · Cochrane
RR 1.99 [1.39, 2.85]NRModerate
Electrical stimulation (plus standard care) vs sham/no ES (plus standard care)
Time to complete healing (3 and 8 weeks) · people with pressure ulcers
Electrical stimulation for treating pressure ulcers (2020) · Cochrane
HR 1.06 [0.47, 2.41]NRVery low
Electrical stimulation (plus standard care) vs sham/no ES (plus standard care)
Complications/ adverse events related to pressure ulcers (3 to 12 weeks) · people with pressure ulcers
Electrical stimulation for treating pressure ulcers (2020) · Cochrane
no estimate extractedNRLow
Electrical stimulation (plus standard care) vs sham/no ES (plus standard care)
Quality of life (QoL) · people with pressure ulcers
Electrical stimulation for treating pressure ulcers (2020) · Cochrane
no estimate extractedNRNo studies
Hydrosurgery vs conventional debridement
Time to complete healing after split‐thickness skin grafting (time to complete healing) · acute partial‐thickness burns prior to skin grafting
Hydrosurgical debridement versus conventional surgical debridement for acute partial‐thickness burns (2020) · Cochrane
no estimate extracted1 study · 61 participantsVery low
Hydrosurgery vs conventional debridement
Postoperative infection (number of participants with post‐operative infection) · acute partial‐thickness burns prior to skin grafting
Hydrosurgical debridement versus conventional surgical debridement for acute partial‐thickness burns (2020) · Cochrane
RR 1.33 [0.57, 3.11]1 study · 61 participantsVery low
Preoperative antibiotics vs placebo or no antibiotic
Wound infections Proportion of wound infections · breast cancer surgery
Prophylactic antibiotics to prevent surgical site infection after breast cancer surgery (2019) · Cochrane
RR 0.67 [0.53, 0.85]10 studies · 2823 participantsModerate
Perioperative antibiotics vs placebo or no antibiotic
Cost of care · breast cancer surgery
Prophylactic antibiotics to prevent surgical site infection after breast cancer surgery (2019) · Cochrane
no estimate extractedNRNo studies
Preoperative antibiotics vs placebo or no antibiotic
Adverse reactions to treatment Proportion of participants with adverse reactions to treatment · breast cancer surgery
Prophylactic antibiotics to prevent surgical site infection after breast cancer surgery (2019) · Cochrane
no estimate extracted10 studies · 2818 participantsVery low
Preoperative antibiotics vs placebo or no antibiotic
Time to onset of infection Mean time to onset of infection · breast cancer surgery
Prophylactic antibiotics to prevent surgical site infection after breast cancer surgery (2019) · Cochrane
no estimate extracted4 studies · 1450 participantsLow
Preoperative antibiotics vs placebo or no antibiotic
Readmission to hospital Proportion of patients readmitted to hospital · breast cancer surgery
Prophylactic antibiotics to prevent surgical site infection after breast cancer surgery (2019) · Cochrane
no estimate extracted3 studies · 784 participantsLow
Preoperative antibiotics vs placebo or no antibiotic
Cost of care Heterogenous cost calculation methodology · breast cancer surgery
Prophylactic antibiotics to prevent surgical site infection after breast cancer surgery (2019) · Cochrane
no estimate extracted2 studies · 510 participantsLow
Perioperative antibiotics vs placebo or no antibiotic
Wound infection Proportion of wound infections · breast cancer surgery
Prophylactic antibiotics to prevent surgical site infection after breast cancer surgery (2019) · Cochrane
RR 0.11 [0.01, 1.95]1 study · 44 participantsVery low
Perioperative antibiotics vs placebo or no antibiotic
Adverse reactions to treatment · breast cancer surgery
Prophylactic antibiotics to prevent surgical site infection after breast cancer surgery (2019) · Cochrane
no estimate extractedNRNo studies
Perioperative antibiotics vs placebo or no antibiotic
Time to onset of infection · breast cancer surgery
Prophylactic antibiotics to prevent surgical site infection after breast cancer surgery (2019) · Cochrane
no estimate extractedNRNo studies
Perioperative antibiotics vs placebo or no antibiotic
Readmission to hospital · breast cancer surgery
Prophylactic antibiotics to prevent surgical site infection after breast cancer surgery (2019) · Cochrane
no estimate extractedNRNo studies
Braden pressure ulcer risk assessment and training vs pressure ulcer risk assessment using clinical judgement and training
Pressure ulcer incidence Visual skin assessment · patients at risk of pressure ulcers
Risk assessment tools for the prevention of pressure ulcers (2019) · Cochrane
RR 0.97 [0.53, 1.77]1 study · 150 participantsVery low
Ramstadius pressure ulcer risk assessment vs pressure ulcer risk assessment using clinical judgement
Severity of new pressure ulcers ‐ Stage 1 · patients at risk of pressure ulcers
Risk assessment tools for the prevention of pressure ulcers (2019) · Cochrane
RR 0.9 [0.48, 1.68]1 study · 820 participantsLow
Ramstadius pressure ulcer risk assessment vs pressure ulcer risk assessment using clinical judgement
Severity of new pressure ulcers ‐ Stage 2 · patients at risk of pressure ulcers
Risk assessment tools for the prevention of pressure ulcers (2019) · Cochrane
RR 0.5 [0.15, 1.65]1 study · 820 participantsLow
Ramstadius pressure ulcer risk assessment vs pressure ulcer risk assessment using clinical judgement
Time to ulcer development Pressure ulcer prevalence · patients at risk of pressure ulcers
Risk assessment tools for the prevention of pressure ulcers (2019) · Cochrane
no estimate extractedNRNo studies
Waterlow pressure ulcer risk assessment vs Ramstadius pressure ulcer risk assessment
Pressure ulcer incidence Visual skin assessment · patients at risk of pressure ulcers
Risk assessment tools for the prevention of pressure ulcers (2019) · Cochrane
RR 1.41 [0.83, 2.39]1 study · 821 participantsLow
Waterlow pressure ulcer risk assessment vs Ramstadius pressure ulcer risk assessment
Severity of new pressure ulcers ‐ Stage 1 · patients at risk of pressure ulcers
Risk assessment tools for the prevention of pressure ulcers (2019) · Cochrane
RR 1.16 [0.63, 2.15]1 study · 821 participantsLow
Waterlow pressure ulcer risk assessment vs Ramstadius pressure ulcer risk assessment
Severity of new pressure ulcers ‐ Stage 2 · patients at risk of pressure ulcers
Risk assessment tools for the prevention of pressure ulcers (2019) · Cochrane
RR 2.49 [0.79, 7.89]1 study · 821 participantsLow
Waterlow pressure ulcer risk assessment vs Ramstadius pressure ulcer risk assessment
Time to ulcer development Pressure ulcer prevalence · patients at risk of pressure ulcers
Risk assessment tools for the prevention of pressure ulcers (2019) · Cochrane
no estimate extractedNRNo studies
Braden pressure ulcer risk assessment and training vs pressure ulcer risk assessment using clinical judgement and training
Severity of new pressure ulcers Time to ulcer development Pressure ulcer prevalence · patients at risk of pressure ulcers
Risk assessment tools for the prevention of pressure ulcers (2019) · Cochrane
no estimate extractedNRNo studies
Braden pressure ulcer risk assessment and training vs pressure ulcer risk assessment using clinical judgement alone
Pressure ulcer incidence Visual skin assessment · patients at risk of pressure ulcers
Risk assessment tools for the prevention of pressure ulcers (2019) · Cochrane
RR 1.43 [0.77, 2.68]1 study · 180 participantsVery low
Braden pressure ulcer risk assessment and training vs pressure ulcer risk assessment using clinical judgement alone
Severity of new pressure ulcers Time to ulcer development Pressure ulcer prevalence · patients at risk of pressure ulcers
Risk assessment tools for the prevention of pressure ulcers (2019) · Cochrane
no estimate extractedNRNo studies
Waterlow pressure ulcer risk assessment vs pressure ulcer risk assessment using clinical judgement
Pressure ulcer incidence Visual skin assessment · patients at risk of pressure ulcers
Risk assessment tools for the prevention of pressure ulcers (2019) · Cochrane
RR 1.1 [0.68, 1.81]1 study · 821 participantsLow
Waterlow pressure ulcer risk assessment vs pressure ulcer risk assessment using clinical judgement
Severity of new pressure ulcers ‐ Stage 1 · patients at risk of pressure ulcers
Risk assessment tools for the prevention of pressure ulcers (2019) · Cochrane
RR 1.05 [0.58, 1.9]1 study · 821 participantsLow
Waterlow pressure ulcer risk assessment vs pressure ulcer risk assessment using clinical judgement
Severity of new pressure ulcers ‐ Stage 2 · patients at risk of pressure ulcers
Risk assessment tools for the prevention of pressure ulcers (2019) · Cochrane
RR 1.25 [0.5, 3.13]1 study · 821 participantsLow
Waterlow pressure ulcer risk assessment vs pressure ulcer risk assessment using clinical judgement
Time to ulcer development Pressure ulcer prevalence · patients at risk of pressure ulcers
Risk assessment tools for the prevention of pressure ulcers (2019) · Cochrane
no estimate extractedNRNo studies
Ramstadius pressure ulcer risk assessment vs pressure ulcer risk assessment using clinical judgement
Pressure ulcer incidence Visual skin assessment · patients at risk of pressure ulcers
Risk assessment tools for the prevention of pressure ulcers (2019) · Cochrane
RR 0.79 [0.46, 1.35]1 study · 820 participantsLow
Primary closure vs no closure
Time to complete wound healing · patients with traumatic wounds due to dog bite
​Primary closure versus delayed or no closure for traumatic wounds due to mammalian bite (2019) · Cochrane
no estimate extractedNRNo studies
Primary closure vs no closure
Proportion of wounds which were infection‐free · patients with traumatic wounds due to dog bite
​Primary closure versus delayed or no closure for traumatic wounds due to mammalian bite (2019) · Cochrane
RR 1.01 [0.97, 1.05]2 studies · 782 participantsVery low
Primary closure vs no closure
Proportion of wounds which were infection‐free · patients with traumatic wounds due to dog bite
​Primary closure versus delayed or no closure for traumatic wounds due to mammalian bite (2019) · Cochrane
no estimate extractedNRNo studies