Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

563 questions · 568 findings · 104 reviews · Headline outcomes only

No studies found 53 · 9.3%GRADE not reported 26 · 4.6%Very low 85 · 15%Low 214 · 37.7%Moderate 151 · 26.6%High 39 · 6.9%

Ambroxol vs placebo or no treatment

Other events in newborns ‐ Administration of pulmonary surfactant frequency in newborns · women at risk of preterm birth

Ambroxol showed no clear difference in other events in newborns ‐ Administration of pulmonary surfactant… compared with placebo or no treatment (low certainty).

1 finding from 1 review

Ambroxol vs placebo or no treatment

Other events in newborns ‐ Need for mechanical ventilation frequency inf newborns · women at risk of preterm birth

Ambroxol showed no clear difference in other events in newborns ‐ Need for mechanical ventilation frequency… compared with placebo or no treatment (low certainty).

1 finding from 1 review

Intervention not reported

Invasive infection prior to hospital discharge · very preterm (< 32 weeks' gestation) or very low birth weight (< 1500 g) infants

The intervention probably leads to higher invasive infection prior to hospital discharge (moderate certainty).

1 finding from 1 review