Question · asked by 1 review

Ambroxol vs placebo or no treatment: Other events in newborns ‐ Administration of pulmonary surfactant frequency in newborns

Population
women at risk of preterm birth
Intervention
Ambroxol
Comparison
placebo or no treatment
Outcome
Other events in newborns ‐ Administration of pulmonary surfactant frequency in newborns

Ambroxol showed no clear difference in other events in newborns ‐ Administration of pulmonary surfactant… compared with placebo or no treatment (low certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Ambroxol vs placebo or no treatment
Other events in newborns ‐ Administration of pulmonary surfactant frequency in newborns · pregnant women at risk of preterm birth for preventing neonatal respiratory distress syndrome
Ambroxol showed no clear difference in other events in newborns ‐ Administration of pulmonary surfactant… compared with placebo or no treatment (low certainty).
Ambroxol for women at risk of preterm birth for preventing neonatal respiratory distress syndrome (2014) · Cochrane Headline outcomes only
RR 1.19 [0.61, 2.3]1 study · 88 participantsLow

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Ambroxol for women at risk of preterm birth for preventing neonatal respiratory distress syndrome
2014 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.