Cochrane · systematic review · CD001970
Delayed introduction of progressive enteral feeds to prevent necrotising enterocolitis in very low birth weight infants
Young, L, Oddie, SJ, McGuire, W · Cochrane Database of Systematic Reviews · 2022 · Cochrane Library
NeonatalAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
4
current version
GRADE rated
4
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 3 · 75%Moderate 1 · 25%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Delayed introduction of progressive enteral feeds to prevent necrotising enterocolitis in very preterm or very low birth weight infants
Population: very preterm (< 32 weeks' gestation) or very low birth weight (< 1500 g) infants
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Necrotising enterocolitis prior to hospital discharge | RR 0.81 | 13 studies · 1507 participants | Low Downgraded: risk of bias |
Mortality prior to hospital discharge | RR 0.97 [0.7, 1.36] | 12 studies · 1399 participants | Low Downgraded: risk of bias |
Feed intolerance prior to hospital discharge | RR 0.81 [0.68, 0.97] | 6 studies · 581 participants | Low Downgraded: risk of bias |
Invasive infection prior to hospital discharge | RR 1.44 [1.15, 1.8] | 7 studies · 872 participants | Moderate Downgraded: risk of bias |