Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,678 questions · 4,859 findings · 283 reviews

No studies found 1,225 · 25.2%GRADE not reported 215 · 4.4%Very low 1,241 · 25.5%Low 1,210 · 24.9%Moderate 776 · 16%High 192 · 4%

SUMMARY OF FINDINGS FOR FUSION vs INTERSPINOUS SPACERS

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · patients with lumbar stenosis

SUMMARY OF FINDINGS FOR FUSION showed no clear difference in pain Long‐term (≥ 12 months) Pain scores converted to 0 to 100 scale… compared with INTERSPINOUS SPACERS (low certainty).

1 finding from 1 review

SUMMARY OF FINDINGS FOR FUSION vs INTERSPINOUS SPACERS

Disability Long‐term (≥ 12 months) Disability scores converted to 0 to 100 scale to allow for comparison of different disability scales (RMDQ, ODI, JOA) · patients with lumbar stenosis

SUMMARY OF FINDINGS FOR FUSION may leads to higher disability Long‐term (≥ 12 months) Disability scores converted to 0… compared with INTERSPINOUS SPACERS (low certainty).

1 finding from 1 review

SUMMARY OF FINDINGS FOR FUSION vs INTERSPINOUS SPACERS

Total operative and perioperative blood loss (mL) ( · patients with lumbar stenosis

SUMMARY OF FINDINGS FOR FUSION probably leads to higher blood loss Amount of perioperative blood loss reported in mL compared with INTERSPINOUS SPACERS (moderate certainty).

1 finding from 1 review

Glutamine vs placebo

Incidence of hepatic veno‐occlusive disease ( · People undergoing stem cell transplant with haematological malignancies

It is very uncertain whether summary of findings: Glutamine changes incidence of hepatic veno‐occlusive disease ( compared with placebo (very low certainty).

1 finding from 1 review

Glutamine vs placebo

All‐cause mortality at 100 days post‐transplant · People undergoing stem cell transplant with haematological malignancies

It is very uncertain whether summary of findings: Glutamine changes all‐cause mortality at 100 days post‐transplant ( compared with placebo (very low certainty).

1 finding from 1 review

Glutamine vs placebo

Mortality attributable to hepatic veno‐occlusive disease ( · People undergoing stem cell transplant with haematological malignancies

It is very uncertain whether summary of findings: Glutamine changes mortality attributable to hepatic veno‐occlusive disease ( compared with placebo (very low certainty).

1 finding from 1 review