Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,155 questions · 1,191 findings · 195 reviews · Headline outcomes only

No studies found 209 · 17.5%GRADE not reported 51 · 4.3%Very low 256 · 21.5%Low 273 · 22.9%Moderate 284 · 23.8%High 118 · 9.9%

Any antihypertensive drug vs no antihypertensive drugs/placebo

Total reported fetal or neonatal deaths (including miscarriage) · women with mild to moderate hypertension during pregnancy

Any antihypertensive drug showed no clear difference in total reported fetal or neonatal deaths (including miscarriage) compared with no antihypertensive drugs/placebo (moderate certainty).

1 finding from 1 review

Any antihypertensive drug vs no antihypertensive drugs/placebo

Small‐for‐gestational age · women with mild to moderate hypertension during pregnancy

Any antihypertensive drug showed no clear difference in small‐for‐gestational age compared with no antihypertensive drugs/placebo (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ Deep neuromuscular blockade (NMB) vs moderate NMB

All‐cause mortality short‐term · adults undergoing intra‐ and transperitoneal laparoscopic procedures

It is very uncertain whether summary of findings table ‐ Deep neuromuscular blockade (NMB) changes all‐cause mortality short‐term compared with moderate NMB (very low certainty).

1 finding from 1 review

Summary of findings table ‐ Deep neuromuscular blockade (NMB) vs moderate NMB

Serious adverse events (SAEs) start of surgery until 8 hours after surgery · adults undergoing intra‐ and transperitoneal laparoscopic procedures

It is very uncertain whether summary of findings table ‐ Deep neuromuscular blockade (NMB) changes serious adverse events (SAEs) start of surgery until 8 hours after… compared with moderate NMB (very low certainty).

1 finding from 1 review

Summary of findings table ‐ Deep neuromuscular blockade (NMB) vs moderate NMB

Short‐term serious adverse events (SAEs) · adults undergoing intra‐ and transperitoneal laparoscopic procedures

It is very uncertain whether summary of findings table ‐ Deep neuromuscular blockade (NMB) changes short‐term serious adverse events (SAEs) compared with moderate NMB (very low certainty).

1 finding from 1 review

Some components of shared decision‐making, including clarification of values and preferences, vs control

Knowledge of all the options · women aged 38 to 71 years at average to moderate risk of breast cancer

Some components of shared decision‐making, including clarification… showed no clear difference in knowledge of all the options compared with control (low certainty).

1 finding from 1 review

Some components of shared decision‐making, including clarification of values and preferences, vs control

Choice of an option aligned with each woman’s values and preferences · women aged 38 to 71 years at average to moderate risk of breast cancer

The review found no eligible studies for this question.

1 finding from 1 review

Some components of shared decision‐making, including clarification of values and preferences, vs control

Mental health outcomes · women aged 38 to 71 years at average to moderate risk of breast cancer

Some components of shared decision‐making, including clarification… showed no clear difference in mental health outcomes compared with control (low certainty).

1 finding from 1 review

Studies focused only on enhanced communication, without clarification of values and preferences, vs control

Confidence in the decision made · women aged 40 to 75 years at average to moderate risk of breast cancer

Studies focused only on enhanced communication, without… showed no clear difference in confidence in the decision made compared with control (low certainty).

1 finding from 1 review

Studies focused only on enhanced communication, without clarification of values and preferences, vs control

Knowledge of all the options · women aged 40 to 75 years at average to moderate risk of breast cancer

Studies focused only on enhanced communication, without… leads to higher knowledge of all the options*** compared with control (high certainty).

1 finding from 1 review

Studies focused only on enhanced communication, without clarification of values and preferences, vs control

Choice of an option aligned with each woman’s values and preferences · women aged 40 to 75 years at average to moderate risk of breast cancer

The review found no eligible studies for this question.

1 finding from 1 review