Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,156 questions · 1,179 findings · 198 reviews · Headline outcomes only

No studies found 250 · 21.2%GRADE not reported 43 · 3.6%Very low 236 · 20%Low 395 · 33.5%Moderate 208 · 17.6%High 47 · 4%

Clobazam vs phenytoin

Retention [ · drug‐naïve people with focal or generalized seizures with solitary cysticercus granuloma

Clobazam may leads to higher retention at 6 months (measured by the number of treatment failures… compared with phenytoin (low certainty).

1 finding from 1 review

Acupuncture vs sham

Changes of medication for gastroparesis (either short or long term) ‐ not measured · symptomatic gastroparesis

The review found no eligible studies for this question.

1 finding from 1 review

RISPERIDONE vs CLOZAPINE ‐ all data short term

Adherence to antipsychotic medication: discontinued medication · people with both severe mental illness and substance misuse

It is very uncertain whether RISPERIDONE changes adherence to antipsychotic medication: discontinued medication compared with CLOZAPINE ‐ all data short term (very low certainty).

1 finding from 1 review

Ketorolac vs placebo

Use of rescue medication · children with acute postoperative pain

It is very uncertain whether ketorolac changes participants using rescue medication in the PACU compared with placebo (very low certainty).

1 finding from 1 review

Intravenous diclofenac vs NSAIDs

Number of participants using rescue medication over 4 to 6 hours postinterventions · Adults (mean study ages 25 to 55 years) with acute postoperative pain after dental, mixed minor, abdominal, or orthopedic surgeries

It is very uncertain whether intravenous diclofenac changes number of participants using rescue medication over 4 to 6 hours… compared with another NSAID (very low certainty).

1 finding from 1 review

Intravenous diclofenac vs placebo

Number of participants using rescue medication over 4 to 6 hours postinterventions · Adults (mean study ages 25 to 55 years) with acute postoperative pain after dental, mixed minor, abdominal, or orthopedic surgeries

Intravenous diclofenac may leads to lower number of participants using rescue medication over 4 to 6 hours… compared with placebo (low certainty).

1 finding from 1 review