Stage at diagnosis (early-stage detection) · Apparently healthy adults aged 35 years or older (general population), living in 13 clusters in rural areas of Trivandrum city, Kerala,…
Visual screening (oral visual inspection) by trained health workers led to lower stage at diagnosis (early-stage detection) compared with no screening; GRADE not reported.
2 findings from 1 review
Leaving the study early/ loss to · people with psychosis
1 finding from 1 review
Occurrence of CIP/CIM ‐ in the total population randomised · critically ill patients
Early physical therapy showed no clear difference in occurrence of CIP/CIM ‐ in the total population randomised compared with control (low certainty).
1 finding from 1 review
Occurrence of CIP/CIM ‐ in screened population · critically ill patients
Early physical therapy probably leads to lower occurrence of CIP/CIM ‐ in screened population compared with control (moderate certainty).
1 finding from 1 review
Serious adverse events ‐ in total population randomised · critically ill patients
Early physical therapy showed no clear difference in serious adverse events ‐ in total population randomised compared with control (moderate certainty).
1 finding from 1 review
Hearing ‐ return to normal *Ventilation tubes versus laser myringotomy (6 to 12 months ‐ medium‐term) Adjusted for non‐independence of within‐individual measurements Assumed ICC of 0.5 № of participants: 132 (2 RCTs) · children aged 6 months to 12 years with otitis media with effusion (OME)
It is very uncertain whether early ventilation tubes changes hearing ‐ return to normal hearing Randomised by child compared with watchful waiting (treatment later if required) (very low certainty).
1 finding from 1 review
RR 0.98 [0.94, 1.03]
Studies not reported
Very low
Disease‐specific quality of life · children aged 6 months to 12 years with otitis media with effusion (OME)
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Presence/persistence of OME · children aged 6 months to 12 years with otitis media with effusion (OME)
It is very uncertain whether early ventilation tubes changes presence/persistence of OME Randomised by child compared with watchful waiting (treatment later if required) (very low certainty).
1 finding from 1 review
RR 1.21 [0.84, 1.74]
Studies not reported
Very low
Adverse event: persistent perforation · children aged 6 months to 12 years with otitis media with effusion (OME)
It is very uncertain whether early ventilation tubes changes adverse event: persistent perforation compared with watchful waiting (treatment later if required) (very low certainty).
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Death by AKI aetiology: non‐surgical causes · AKI
Subgroup analyses: early showed no clear difference in death by AKI aetiology: non‐surgical causes compared with standard initiation of kidney replacement therapy (KRT) (moderate certainty).
1 finding from 1 review
Death by AKI aetiology: surgical causes · AKI
Subgroup analyses: early showed no clear difference in death by AKI aetiology: surgical causes compared with standard initiation of kidney replacement therapy (KRT) (low certainty).
1 finding from 1 review
Kidney recovery functionby KRT: continuous KRT · AKI
Subgroup analyses: early showed no clear difference in kidney recovery functionby KRT: continuous KRT compared with standard initiation of kidney replacement therapy (KRT) (moderate certainty).
1 finding from 1 review
Kidney recovery functionby KRT: continuous and intermittent KRT · AKI
Subgroup analyses: early showed no clear difference in kidney recovery functionby KRT: continuous and intermittent KRT compared with standard initiation of kidney replacement therapy (KRT) (moderate certainty).
1 finding from 1 review
Mortality ( · small asymptomatic AAA
Early endovascular repair showed no clear difference in mortality ( compared with ultrasound surveillance (low certainty).
1 finding from 1 review
Costs · small asymptomatic AAA
Early endovascular repair showed no clear difference in costs ( compared with ultrasound surveillance (low certainty).
2 findings from 1 review
QoL · small asymptomatic AAA
1 finding from 1 review
Aneurysm rupture ( · small asymptomatic AAA
1 finding from 1 review
Global state: average score: long term (+ 26 weeks) Global Assessment Scale (GAS). Scale from: 0 to 100. · patients with schizophrenia
1 finding from 1 review
Mental state · patients with schizophrenia
1 finding from 1 review
Adverse effects: tardive dyskinesia: long term (+ 26 weeks) as defined in each study · patients with schizophrenia
INTERMITTENT (EARLY‐BASED) showed no clear difference in adverse effects: tardive dyskinesia: long term (+26 weeks) as… compared with MAINTENANCE THERAPY (low certainty).
1 finding from 1 review