What do systematic reviews say?

Summary of findings table ‐ LSSS intervention vs regular salt

Summary of findings table ‐ LSSS intervention showed no clear difference in hypertension compared with regular salt (low certainty).

• Replacing salt with low‐sodium salt substitutes (LSSS) for cardiovascular health in adults, children and pregnant women 2022 · Cochrane Headline outcomes only
  RR 0.97 [0.9, 1.03]
  1 study · 2566 participants
  Low

Summary of findings table ‐ LSSS intervention vs regular salt

It is very uncertain whether summary of findings table ‐ LSSS intervention changes blood pressure control compared with regular salt (very low certainty).

• Replacing salt with low‐sodium salt substitutes (LSSS) for cardiovascular health in adults, children and pregnant women 2022 · Cochrane Headline outcomes only
  RR 2.12 [1.32, 3.41]
  2 studies · 253 participants
  Very low

Summary of findings table ‐ LSSS intervention vs regular salt

It is very uncertain whether summary of findings table ‐ LSSS intervention changes cardiovascular events: various compared with regular salt (very low certainty).

• Replacing salt with low‐sodium salt substitutes (LSSS) for cardiovascular health in adults, children and pregnant women 2022 · Cochrane Headline outcomes only
  RR 1.22 [0.49, 3.04]
  5 studies · 982 participants
  Very low

Summary of findings table ‐ LSSS intervention vs regular salt

Summary of findings table ‐ LSSS intervention showed no clear difference in cardiovascular events: non‐fatal stroke compared with regular salt (moderate certainty).

• Replacing salt with low‐sodium salt substitutes (LSSS) for cardiovascular health in adults, children and pregnant women 2022 · Cochrane Headline outcomes only
  RR 0.9 [0.8, 1.01]
  3 studies · 21250 participants
  Moderate

Summary of findings table ‐ LSSS intervention vs regular salt

Summary of findings table ‐ LSSS intervention probably leads to lower cardiovascular events: non‐fatal acute coronary syndrome (events per… compared with regular salt (moderate certainty).

• Replacing salt with low‐sodium salt substitutes (LSSS) for cardiovascular health in adults, children and pregnant women 2022 · Cochrane Headline outcomes only
  Rate ratio 0.7 [0.52, 0.94]
  1 study · 20995 participants
  Moderate

Summary of findings table ‐ LSSS intervention vs regular salt

Summary of findings table ‐ LSSS intervention showed no clear difference in cardiovascular mortality (events per 100,000 person‐years) compared with regular salt (moderate certainty).

• Replacing salt with low‐sodium salt substitutes (LSSS) for cardiovascular health in adults, children and pregnant women 2022 · Cochrane Headline outcomes only
  Rate ratio 0.77 [0.6, 1]
  3 studies · 23200 participants
  Moderate

Summary of findings table ‐ LSSS intervention vs regular salt

It is very uncertain whether summary of findings table ‐ LSSS intervention changes stroke mortality (events per 100,000 person‐years) compared with regular salt (very low certainty).

• Replacing salt with low‐sodium salt substitutes (LSSS) for cardiovascular health in adults, children and pregnant women 2022 · Cochrane Headline outcomes only
  Rate ratio 0.64 [0.33, 1.25]
  2 studies · 21423 participants
  Very low

Intervention not reported

The intervention probably leads to higher complete clot lysis (intermediate, 6 months to under 5 years after… (moderate certainty).

• Thrombolytic strategies versus standard anticoagulation for acute deep vein thrombosis of the lower limb 2021 · Cochrane Headline outcomes only
  RR 2.42 [1.42, 4.12]
  7 studies · 654 participants
  Moderate

Intervention not reported

The intervention probably leads to higher bleeding (early, up to 1 month after treatment) (moderate certainty).

• Thrombolytic strategies versus standard anticoagulation for acute deep vein thrombosis of the lower limb 2021 · Cochrane Headline outcomes only
  RR 2.45 [1.58, 3.78]
  19 studies · 1943 participants
  Moderate

Intervention not reported

The intervention probably leads to lower post‐thrombotic syndrome (intermediate, 6 months to under 5 years… (moderate certainty).

• Thrombolytic strategies versus standard anticoagulation for acute deep vein thrombosis of the lower limb 2021 · Cochrane Headline outcomes only
  RR 0.78 [0.66, 0.93]
  6 studies · 1393 participants
  Moderate

Intervention not reported

The intervention probably leads to lower post‐thrombotic syndrome (late, 5 years (moderate certainty).

• Thrombolytic strategies versus standard anticoagulation for acute deep vein thrombosis of the lower limb 2021 · Cochrane Headline outcomes only
  RR 0.56 [0.43, 0.73]
  2 studies · 211 participants
  Moderate

Postoperative use of LNG‐IUD vs postoperative GnRH‐a

• Levonorgestrel‐releasing intrauterine device (LNG‐IUD) for symptomatic endometriosis following surgery 2021 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 40 participants
  Very low

Postoperative use of LNG‐IUD vs postoperative GnRH‐a

• Levonorgestrel‐releasing intrauterine device (LNG‐IUD) for symptomatic endometriosis following surgery 2021 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 18 participants
  Very low

Postoperative use of LNG‐IUD vs postoperative GnRH‐a

The review found no eligible studies for this question.

• Levonorgestrel‐releasing intrauterine device (LNG‐IUD) for symptomatic endometriosis following surgery 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Postoperative use of LNG‐IUD vs postoperative GnRH‐a

The review found no eligible studies for this question.

• Levonorgestrel‐releasing intrauterine device (LNG‐IUD) for symptomatic endometriosis following surgery 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Postoperative use of LNG‐IUD vs postoperative GnRH‐a

The review found no eligible studies for this question.

• Levonorgestrel‐releasing intrauterine device (LNG‐IUD) for symptomatic endometriosis following surgery 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Postoperative use of LNG‐IUD vs postoperative GnRH‐a

• Levonorgestrel‐releasing intrauterine device (LNG‐IUD) for symptomatic endometriosis following surgery 2021 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 40 participants
  Very low

Postoperative use of LNG‐IUD vs postoperative GnRH‐a

The review found no eligible studies for this question.

• Levonorgestrel‐releasing intrauterine device (LNG‐IUD) for symptomatic endometriosis following surgery 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Postoperative use of LNG‐IUD vs postoperative GnRH‐a

The review found no eligible studies for this question.

• Levonorgestrel‐releasing intrauterine device (LNG‐IUD) for symptomatic endometriosis following surgery 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Intervention not reported

The review found no eligible studies for this question.

• Paying for performance to improve the delivery of health interventions in low‐ and middle‐income countries 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found